The invention provides a novel class of cyanine dyes that are functionalized with sulfonic acid groups and a linker moiety that facilitates their conjugation to other species and substituent groups which increase the water-solubility, and optimize the optical properties of the dyes. Also provided are conjugates of the dyes, methods of using the dyes and their conjugates and kits including the dyes and their conjugates.
本发明提供了一种新型的靛绿
染料类,其具有
磺酸基团和连接基团的官能化,并且这些连接基团有助于将它们与其他物种和取代基团共轭,并增加了
染料的
水溶性和优化了光学性质。同时还提供了这些
染料的共轭物、使用这些
染料及其共轭物的方法,以及包括这些
染料及其共轭物的试剂盒。