cis-dichloro(methionine)platinum(II) | 31674-58-5

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: cis-dichloro(methionine)platinum(II)
• 英文别名: Platinum(2+) chloride 2-amino-4-(methylsulfanyl)butanoate--hydrogen chloride (1/1/1/1)；2-amino-4-methylsulfanylbutanoate;platinum(2+);chloride;hydrochloride
• CAS: 31674-58-5
• 化学式: C₅H₁₁Cl₂NO₂PtS
• 分子量: 415.2
• InChiKey: KUUWJEBNGYSFNN-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  -7.07
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  91.4
• 氢给体数：
  2
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  cis-dichloro(methionine)platinum(II) 在 五氯化磷 作用下， 以 氯仿 为溶剂， 生成 Tetrachloro-(methionylchlorid)-platin(IV)
  参考文献：
  名称：

  Purucker,B.; Beck,W., Chemische Berichte, 1974, vol. 107, p. 3476 - 3485

  摘要：

  DOI：

文献信息

• Khan, Badar Taqui; Mohan, K Murali; Goud, G Narsa, Indian Journal of Chemistry, Section A: Inorganic, Physical, Theoretical and Analytical, 1992, vol. 31, # 1.2, p. 106 - 109
  作者：Khan, Badar Taqui、Mohan, K Murali、Goud, G Narsa

  DOI：——

  日期：——
• Khan, Badar Taqui; Mohan, K. Murali; Khan, S. Rounaq Ali, Indian Journal of Chemistry, Section A: Inorganic, Physical, Theoretical and Analytical, 1995, vol. 34, # 7, p. 573 - 575
  作者：Khan, Badar Taqui、Mohan, K. Murali、Khan, S. Rounaq Ali、Goud, G. Narsa

  DOI：——

  日期：——
• Mixed ligand complexes of cis-dichloromethionineplatinum(II) and cis-dichloromethioninepalladium(II) with substituted pyrimidines
  作者：Badar Taqui Khan、T.K. Annapoorna、S. Shamsuddin、K. Najmuddin

  DOI：10.1016/s0277-5387(00)83168-x

  日期：1992.1

  Mixed ligand complexes of cis-dichloromethionineplatinum(II), [Pt(meth)Cl2], with pyrimidines, 2-hydroxypyrimidinehydrochloride, 5-aminouracil, 2-thiocytosine, isocytosine and mixed ligand complexes of cis-dichloromethioninepalladium(II), [Pd(meth)Cl2], with pyrimidines, 2-hydroxypyrimidinchydrochloride, 5-aminouracil and 4,6-diamino-2-thiopyrimidine were synthesized and characterized by elemental analysis, IR, UV, H-1 NMR and C-13 NMR spectra. In these mixed ligand complexes methionine coordinates to the metal ion through sulphur and the amino nitrogen, thus leaving a free carboxylic acid group. The pyrimidines, 2-hydroxypyrimidinehydrochloride, 4,6-diamino-2-thiopyrimidine, isocytosine and 2-thiocytosine act as monodentate ligands and bind to the metal ion through N3, while 5-aminouracil coordinates to the metal ion through the amino (NH2) group.
• Purucker,B.; Beck,W., Chemische Berichte, <hi>1974</hi>, vol. 107, p. 3476 - 3485
  作者：Purucker,B.、Beck,W.

  DOI：——

  日期：——