N-[2-(carboxymethoxy)ethyl]glycine | 313672-62-7

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: N-[2-(carboxymethoxy)ethyl]glycine
• 英文别名: 2-[2-(Carboxymethoxy)ethylamino]acetic acid
• CAS: 313672-62-7
• 化学式: C₆H₁₁NO₅
• 分子量: 177.157
• InChiKey: VOIILENOTKZILS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.4
• 重原子数：
  12
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  95.9
• 氢给体数：
  3
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  N-[2-(carboxymethoxy)ethyl]glycine 、 氰基甲醇 甲醛氰醇 生成 N-[2-(carboxymethoxy)ethyl]-N-(cyanomethyl)glycine
  参考文献：
  名称：

  Intermediates for the preparation of N-[2-(carboxymethoxy)ethyl]-N-(carboxymethyl)glycine

  摘要：

  公式表示的化合物为其中R和R1独立地表示H、—CH2CN或—CH2CO2X，但R和R1不能同时为H或—CH2CO2X；X表示氢、碱金属或碱土金属。这些化合物可用作制备N-[2-(羧甲氧基)乙基]-N-(羧甲基)甘氨酸的中间化合物。这些中间体可以通过在碱性条件下将3-吗啉酮与甘腈接触形成氨基腈，再水解并与额外的甘腈接触形成腈中间体，然后通过水解将腈中间体转化为N-[2-(羧甲氧基)乙基]-N-(羧甲基)甘氨酸。

  公开号：

  US06288263B1
• 作为产物：
  描述：

  N-[2-(carboxymethoxy)ethyl]aminoacetonitrile 生成 N-[2-(carboxymethoxy)ethyl]glycine
  参考文献：
  名称：

  Intermediates for the preparation of N-[2-(carboxymethoxy)ethyl]-N-(carboxymethyl)glycine

  摘要：

  公式表示的化合物为其中R和R1独立地表示H、—CH2CN或—CH2CO2X，但R和R1不能同时为H或—CH2CO2X；X表示氢、碱金属或碱土金属。这些化合物可用作制备N-[2-(羧甲氧基)乙基]-N-(羧甲基)甘氨酸的中间化合物。这些中间体可以通过在碱性条件下将3-吗啉酮与甘腈接触形成氨基腈，再水解并与额外的甘腈接触形成腈中间体，然后通过水解将腈中间体转化为N-[2-(羧甲氧基)乙基]-N-(羧甲基)甘氨酸。

  公开号：

  US06288263B1

文献信息

• Intermediates for the preparation of N-[2-(carboxymethoxy) ethyl]-N-(carboxymethyl) glycine
  申请人：The Dow Chemical Company

  公开号：US06392095B2

  公开（公告）日：2002-05-21

  Compounds represented by the formula wherein R and R1 independently represent H, —CH2CN or —CH2CO2X, with the proviso that R and R1 can not be both H or —CH2CO2X; and X represents hydrogen, an alkali metal or alkaline earth metal are disclosed. These compounds are useful as intermediate compounds in the preparation of N-[2-(carboxymethoxy)ethyl]-N-(carboxy-methyl)glycine. These intermediates can be formed by contacting 3-morpholinone with glycolonitrile under alkaline conditions to form an aminonitrile which can be hydrolyzed and contacted with additional glycolonitrile to form the nitrile intermediate which can be converted to N-[2-(carboxymethoxy)ethyl]-N-(carboxymethyl)glycine via hydrolysis.

  公式表示的化合物中，其中R和R1分别表示H、—CH2CN或—CH2CO2X，但R和R1不能同时为H或—CH2CO2X；X表示氢、碱金属或碱土金属。这些化合物可作为N-[2-(羧甲氧基)乙基]-N-(羧甲基)甘氨酸制备中间体化合物。这些中间体可以通过在碱性条件下将3-吗啉酮与甘氰酸接触以形成氨基腈，然后水解并与额外的甘氰酸接触以形成腈中间体，最后通过水解将腈中间体转化为N-[2-(羧甲氧基)乙基]-N-(羧甲基)甘氨酸。
• Intermediates for the preparation of N-[2-(carboxymethoxy) ethyl]-N-(carboxymethyl) glycine
  申请人：——

  公开号：US20020010367A1

  公开（公告）日：2002-01-24

  Compounds represented by the formula 1 wherein R and R 1 independently represent H, —CH 2 CN or —CH 2 CO 2 X, with the proviso that R and R 1 can not be both H or —CH 2 CO 2 X; and X represents hydrogen, an alkali metal or alkaline earth metal are disclosed. These compounds are useful as intermediate compounds in the preparation of N-[2-(carboxymethoxy)ethyl]-N-(carboxy-methyl)glycine. These intermediates can be formed by contacting 3-morpholinone with glycolonitrile under alkaline conditions to form an aminonitrile which can be hydrolyzed and contacted with additional glycolonitrile to form the nitrile intermediate which can be converted to N-[2-(carboxymethoxy)ethyl]-N-(carboxymethyl)glycine via hydrolysis.

  本发明涉及一种由式1表示的化合物，其中R和R1分别独立表示H、—CH2CN或—CH2CO2X，但R和R1不能同时为H或—CH2CO2X；X表示氢、碱金属或碱土金属。这些化合物可用作制备N-［2-（羧甲氧基）乙基］-N-（羧甲基）甘氨酸的中间化合物。这些中间体可以通过在碱性条件下将3-吗啉酮与甘腈接触以形成氨基腈，然后水解并与额外的甘腈接触以形成腈中间体，然后通过水解将其转化为N-［2-（羧甲氧基）乙基］-N-（羧甲基）甘氨酸。
• Methods and compositions for treating a subterranean formation with a polymeric additive composite
  申请人：Halliburton Energy Services, Inc.

  公开号：US10723939B2

  公开（公告）日：2020-07-28

  Methods and compositions for treating a subterranean formation are provided. The method can include introducing a treatment fluid into the subterranean formation containing an aqueous downhole fluid. The treatment fluid can contain one or more polymers, a particulate additive containing one or more additives, and one or more organic solvents. The polymer is at least partially dissolved in the organic solvent and the particulate additive is at least partially suspended in the organic solvent. The method can also include combining the treatment fluid with the aqueous downhole fluid to produce a polymeric additive composite and a fluid mixture within the subterranean formation. The polymeric additive composite contains the particulate additive at least partially embedded in the polymer to prevent an uncontrolled release of the particulate additive into the fluid mixture.

  提供了处理地下地层的方法和组合物。该方法可包括将处理液引入含有水性井下流体的地下地层。处理液可以包含一种或多种聚合物、含有一种或多种添加剂的微粒添加剂以及一种或多种有机溶剂。聚合物至少部分溶解在有机溶剂中，颗粒添加剂至少部分悬浮在有机溶剂中。该方法还可包括将处理液与水性井下流体结合，在地下地层中产生聚合物添加剂复合体和流体混合物。聚合物添加剂复合体包含至少部分嵌入聚合物中的微粒添加剂，以防止微粒添加剂不受控制地释放到流体混合物中。
• Corrosion Inhibition of HCL Treatment Fluids with Environmentally Compatible Solvent
  申请人：Halliburton Energy Services, Inc.

  公开号：US20200173034A1

  公开（公告）日：2020-06-04

  A method of treating in a subterranean formation including placing a corrosion inhibitor composition into a subterranean formation, where the formation includes an acidic environment having a pH of about 5 or below, where the composition includes: an organic solvent comprising an alcohol with a flash point of at least about 75° C.; a nitrogen containing compound; an aqueous acid solution comprising HCl; and contacting a metal surface with the corrosion inhibitor composition. A corrosion inhibitor composition includes an organic solvent comprising an alcohol with a flash point of at least about 75° C.; a nitrogen containing compound; and an aqueous acid solution comprising HCl.
• US6288263B1
  申请人：——

  公开号：US6288263B1

  公开（公告）日：2001-09-11