(S)-2-(Toluene-4-sulfonylamino)-pentanedioic acid 1-tert-butyl ester 5-(4-vinyl-benzyl) ester | 159046-71-6

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (S)-2-(Toluene-4-sulfonylamino)-pentanedioic acid 1-tert-butyl ester 5-(4-vinyl-benzyl) ester
• CAS: 159046-71-6
• 化学式: C₂₅H₃₁NO₆S
• 分子量: 473.59
• InChiKey: IHUPABNVYPWZKF-QFIPXVFZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.15
• 重原子数：
  33.0
• 可旋转键数：
  10.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  98.77
• 氢给体数：
  1.0
• 氢受体数：
  6.0

反应信息

• 作为反应物：
  描述：

  (S)-2-(Toluene-4-sulfonylamino)-pentanedioic acid 1-tert-butyl ester 5-(4-vinyl-benzyl) ester 在 dowex 作用下， 以 苯 为溶剂， 生成
  参考文献：
  名称：

  Polymer-supported chiral borane promoters for the asymmetric aldol reaction of benzaldehyde with silyl ketene acetal

  摘要：

  Chiral polymers (A and B) having pendant alpha-amino acid moiety were prepared by suspension copolymerization. A polymer-supported chiral borane, formed from chiral polymer A and BH3.THF, effectively promoted the aldol reaction in THF of benzaldehyde with silyl ketene acetal in a similar enantioselectivity to that using the corresponding soluble counterpart. Some interesting polymer effects were also found on solvent and reaction temperature. .

  DOI：

  10.1016/s0040-4039(00)77074-2
• 作为产物：
  描述：

  γ-Benzyl-N-tosyl-L-glutaminsaeureester 在 18-冠醚-6 氢氧化钾 、 sodium hydroxide 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 生成 (S)-2-(Toluene-4-sulfonylamino)-pentanedioic acid 1-tert-butyl ester 5-(4-vinyl-benzyl) ester
  参考文献：
  名称：

  Polymer-supported chiral borane promoters for the asymmetric aldol reaction of benzaldehyde with silyl ketene acetal

  摘要：

  Chiral polymers (A and B) having pendant alpha-amino acid moiety were prepared by suspension copolymerization. A polymer-supported chiral borane, formed from chiral polymer A and BH3.THF, effectively promoted the aldol reaction in THF of benzaldehyde with silyl ketene acetal in a similar enantioselectivity to that using the corresponding soluble counterpart. Some interesting polymer effects were also found on solvent and reaction temperature. .

  DOI：

  10.1016/s0040-4039(00)77074-2