glutathione | 148102-19-6

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: glutathione
• 英文别名: (2S)-2-amino-4-({1-[(carboxymethyl)carbamoyl]-2-sulfanylethyl}carbamoyl)butanoic acid；(2S)-2-amino-5-[[1-(carboxymethylamino)-1-oxo-3-sulfanylpropan-2-yl]amino]-5-oxopentanoic acid
• CAS: 148102-19-6
• 化学式: C₁₀H₁₇N₃O₆S
• 分子量: 307.327
• InChiKey: RWSXRVCMGQZWBV-ZBHICJROSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -4.5
• 重原子数：
  20
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  160
• 氢给体数：
  6
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  tryptamine-4,5-dione N-ethylcarbamate 、 glutathione 以 四氢呋喃 、 水 为溶剂， 生成 (S)-2-Amino-4-{1-(carboxymethyl-carbamoyl)-2-[3-(2-ethoxycarbonylamino-ethyl)-4,5-dioxo-4,5-dihydro-1H-indol-7-ylsulfanyl]-ethylcarbamoyl}-butyric acid
  参考文献：
  名称：

  Preparation, reactivity, and neurotoxicity of tryptamine-4,5-dione

  摘要：

  DOI：

  10.1016/s0040-4039(00)94405-8

文献信息

• MOLECULARLY IMPRINTED POLYMERS FOR THE RECOGNITION OF GLUTATHIONE GSH, METHODS FOR PREPARING SAME AND USES THEREOF
  申请人：Perollier Celine

  公开号：US20100234565A1

  公开（公告）日：2010-09-16

  The present invention relates to new molecularly imprinted polymers which are suitable for the selective recognition of glutathione GSH and/or of an analog thereof, and in particular which are of use for the treatment of media comprising in particular a mixture of glutathione GSH, and/or of an analog thereof, with GSH adducts.

  本发明涉及新的分子印迹聚合物，适用于选择性识别谷胱甘肽GSH和/或其类似物，特别是用于处理包括谷胱甘肽GSH和/或其类似物与GSH加合物的介质。
• Pharmaceutical compounds
  申请人：Soldato Del Piero

  公开号：US20070142342A1

  公开（公告）日：2007-06-21

  Steroidal compounds or their salts having general formulas (I) and (II) wherein: s is an integer equal to 1 or 2, preferably s-2: bO 0 or 1; A═R—, wherein R is the steroidal drug radical, C and C 1 are two bivalent radicals. The precursors of the radicals B and B 1 are such as to meet the pharmacological tests reported in the description.

  具有通式(I)和(II)的类固醇化合物或其盐，其中：s是等于1或2的整数，最好是s-2；bO为0或1；A═R—，其中R为类固醇药物基团，C和C1是两个双价基团。基团B和B1的前体应满足描述中报告的药理学测试。
• A bioreactor, in particular for NMR spectroscopy
  申请人：Bradamante, Silvia

  公开号：EP1500944A1

  公开（公告）日：2005-01-26

  A description is given of a bioreactor (1), in particular for NMR spectroscopy, comprising a container (7) capable of containing a cell culture, a first inlet line (6) for the inward flow of a culture medium to the inside of the container and a second outlet line (9, 10) for the outward flow of the culture medium from the container (7). The first line (6), an inlet line, is connected to a spiral-shaped device (12) which has a form such that when the medium is made to flow inside the first line (6) and made to flow out of the second line (9; 10), hydrostatic thrust and hydrodynamic forces produce with respect to the cells a condition of simulated reduced gravity inside the container (7).

  描述了一种生物反应器 (1)，特别是用于核磁共振光谱分析的生物反应器 (1)，它包括一个能够容纳细胞培养物的容器 (7)，一个用于将培养基导入容器内部的第一进口管路 (6) 和一个用于将培养基从容器 (7) 流出的第二出口管路 (9, 10)。第一进水管（6）与一个螺旋形装置（12）相连，该装置的形状使培养基在第一进水管（6）内流动并从第二出水管（9、10）流出时，静水推力和流体动力在容器（7）内对细胞产生模拟重力减小的状态。
• IMPROVED PROTEIN EXPRESSION STRAINS
  申请人：Albumedix Ltd

  公开号：EP4026908A1

  公开（公告）日：2022-07-13

  The invention provides an improved host strain for production of desired protein.

  本发明提供了一种用于生产所需蛋白质的改良宿主菌株。
• Protein expression strains
  申请人：Albumedix Ltd

  公开号：US11130979B2

  公开（公告）日：2021-09-28

  The invention provides an improved host strain for production of desired protein.

  本发明提供了一种用于生产所需蛋白质的改良宿主菌株。