1,8-bis[(hydroxyethyl)oxy]anthraquinone | 880758-62-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• 英文名称: 1,8-bis[(hydroxyethyl)oxy]anthraquinone
• 英文别名: 1,8-bis(2-hydroxyethoxy)anthraquinone；1,8-Bis(2-hydroxyethoxy)anthracene-9,10-dione
• CAS: 880758-62-3
• 化学式: C₁₈H₁₆O₆
• 分子量: 328.321
• InChiKey: VGBFJIMBMGKBOH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  24
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  93.1
• 氢给体数：
  2
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  1,8-bis[(hydroxyethyl)oxy]anthraquinone 在 正丁基锂 、 对甲苯磺酸 作用下， 以 四氢呋喃 、 正己烷 、 二氯甲烷 为溶剂， 反应 2.5h， 生成 2,2'-((((9,10-bis(4,5-bis(methylthio)-1,3-dithiol-2-ylidene)-9,10-dihydroanthracene-1,8-diyl)bis(oxy))bis(ethane-2,1-diyl))bis(oxy))bis(tetrahydro-2H-pyran)
  参考文献：
  名称：

  Novel 9,10-Bis(1,3-dithiol-2-ylidene)-9,10- dihydroanthracene Derivatives Bridged by a Crown Ether Unit at the 1,8-Positions: A New Type of Redox-switchable Hosts Undergoing Reversible Structural Changes

  摘要：

  Novel redox-switchable host molecules (2) composed of a 9,10-bis(1,3-dithiol-2-ylidene)-9,10-dihydroanthracene unit and a crown ether moiety bridging the 1,8-positions have been synthesized. Cyclic voltammetry and X-Ray analyses revealed that the molecules undergo a significant structural change upon oxidation. 'H-NMR titration experiments on the neutral and dication states show that the binding abilities of the dication states for alkali metal cations (Li+, Na+, K+) are considerably lower than those of the neutral molecules. The binding properties of 2 were also investigated by cyclic voltammetry.

  DOI：

  10.3987/com-05-s(t)55
• 作为产物：
  描述：

  1,8-二羟基蒽醌 在 四丁基溴化铵 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 8.0h， 生成 1,8-bis[(hydroxyethyl)oxy]anthraquinone
  参考文献：
  名称：

  Novel 9,10-Bis(1,3-dithiol-2-ylidene)-9,10- dihydroanthracene Derivatives Bridged by a Crown Ether Unit at the 1,8-Positions: A New Type of Redox-switchable Hosts Undergoing Reversible Structural Changes

  摘要：

  Novel redox-switchable host molecules (2) composed of a 9,10-bis(1,3-dithiol-2-ylidene)-9,10-dihydroanthracene unit and a crown ether moiety bridging the 1,8-positions have been synthesized. Cyclic voltammetry and X-Ray analyses revealed that the molecules undergo a significant structural change upon oxidation. 'H-NMR titration experiments on the neutral and dication states show that the binding abilities of the dication states for alkali metal cations (Li+, Na+, K+) are considerably lower than those of the neutral molecules. The binding properties of 2 were also investigated by cyclic voltammetry.

  DOI：

  10.3987/com-05-s(t)55

文献信息

• Copolymerizable methine and anthraquinone compounds and articles containing them
  申请人：Pearson Clay Jason

  公开号：US20060115516A1

  公开（公告）日：2006-06-01

  This invention relates to polymerizable ultraviolet light absorbers and yellow colorants and their use in ophthalmic lenses. In particular, this invention relates to polymerizable ultraviolet light absorbing methine compounds and yellow compounds of the methine and anthraquinone classes that block ultraviolet light and/or violet-blue light transmission through ophthalmic lenses.

  这项发明涉及可聚合的紫外光吸收剂和黄色染料，以及它们在眼镜镜片中的应用。具体而言，这项发明涉及可聚合的紫外光吸收亚甲基化合物和亚甲基和蒽醌类化合物，这些化合物通过眼镜镜片阻挡紫外光和/或紫蓝光的透射。
• Anthraquinones as Artificial DNA Building Blocks
  作者：Nicolas Bouquin、Vladimir L. Malinovskii、Robert Häner

  DOI：10.1002/ejoc.200800080

  日期：2008.5

  Synthesis and properties of oligodeoxynucleotides containing anthraquinone-derived building blocks with flexible linkers are described. Starting from the 1,4-, 1,5-, 1,8- and 2,6-dihydroxyanthraquinone isomers, the corresponding phosphoramidites were prepared and incorporated into oligonucleotides. The site of linker attachment was found to be of critical importance for hybrid stability. Whereas the

  描述了含有蒽醌衍生结构单元和柔性接头的寡脱氧核苷酸的合成和性质。从 1,4-、1,5-、1,8- 和 2,6- 二羟基蒽醌异构体开始，制备相应的亚磷酰胺并将其掺入寡核苷酸中。发现接头附着位点对于杂交稳定性至关重要。虽然 2,6-异构体导致显着的稳定性，但所有其他异构体对双链体的稳定性有负面影响。光谱研究表明蒽醌类具有荧光猝灭剂的作用。提出了蒽醌修饰的双链杂种模型。(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)
• COPOLYMERIZABLE METHINE AND ANTHRAQUINONE COMPOUNDS AND ARTICLES CONTAINING THEM
  申请人：Abbott Medical Optics Inc.

  公开号：EP1815274B1

  公开（公告）日：2011-09-21
• US8360576B2
  申请人：——

  公开号：US8360576B2

  公开（公告）日：2013-01-29
• US8501890B2
  申请人：——

  公开号：US8501890B2

  公开（公告）日：2013-08-06