4,4'-{[1,2-phenylenebis(methylene)]bis(oxy)}dibenzoic acid | 292824-66-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4,4'-{[1,2-phenylenebis(methylene)]bis(oxy)}dibenzoic acid
• 英文别名: 4,4’-((1,2-phenylenebis(methylene))bis(oxy))dibenzoic acid；4,4′-{[1,2-phenylenebis-(methylene)]bis(oxy)}dibenzoic acid；4,4'-[1,2-Phenylenebis(methyleneoxy)]dibenzoic acid；4-[[2-[(4-carboxyphenoxy)methyl]phenyl]methoxy]benzoic acid
• CAS: 292824-66-9
• 化学式: C₂₂H₁₈O₆
• 分子量: 378.381
• InChiKey: ZKVLOXCDXFVPNX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  28
• 可旋转键数：
  8
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.09
• 拓扑面积：
  93.1
• 氢给体数：
  2
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  4,4'-{[1,2-phenylenebis(methylene)]bis(oxy)}dibenzoic acid 在 氯化亚砜 、 三乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 3.0h， 以82%的产率得到4,4'-((1,2-phenylenebis(methylene))bis(oxy))dibenzoyl chloride
  参考文献：
  名称：

  Synthesis of novel carbazole based macrocyclic amides as potential antimicrobial agents

  摘要：

  A series of carbazole based macrocyclic diamides with thia and oxy linkages have been synthesized and the inhibitory activity of the cyclophane amides against human pathogenic bacteria and plant pathogenic fungi are documented. (S)-1,10-Bi-2-naphthol [(S)-BINOL] based chiral carbazolophane amide emerged as the most interesting compound in this series exhibiting excellent antibacterial and antifungal activities. (C) 2008 Elsevier Masson SAS. All rights reserved.

  DOI：

  10.1016/j.ejmech.2008.07.031
• 作为产物：
  描述：

  Methyl 4-[[2-[(4-methoxycarbonylphenoxy)methyl]phenyl]methoxy]benzoate 在 甲醇 、 氢氧化钾 作用下， 以85%的产率得到4,4'-{[1,2-phenylenebis(methylene)]bis(oxy)}dibenzoic acid
  参考文献：
  名称：

  Synthesis of novel carbazole based macrocyclic amides as potential antimicrobial agents

  摘要：

  A series of carbazole based macrocyclic diamides with thia and oxy linkages have been synthesized and the inhibitory activity of the cyclophane amides against human pathogenic bacteria and plant pathogenic fungi are documented. (S)-1,10-Bi-2-naphthol [(S)-BINOL] based chiral carbazolophane amide emerged as the most interesting compound in this series exhibiting excellent antibacterial and antifungal activities. (C) 2008 Elsevier Masson SAS. All rights reserved.

  DOI：

  10.1016/j.ejmech.2008.07.031
• 作为试剂：
  描述：

  乙腈 、 copper(II) acetate monohydrate 、 4′-(4-pyridyl)-3,2′:6′,3″-terpyridine 在 4,4'-{[1,2-phenylenebis(methylene)]bis(oxy)}dibenzoic acid 作用下， 以 水 为溶剂， 反应 72.5h， 以41%的产率得到[Cu(4′-(4-pyridyl)-3,2′:6′,3″-terpyridine)(CN)]_n
  参考文献：
  名称：

  具有多个路易斯碱性位点的发光二维 Cu(I) 配位聚合物对硝基爆炸物和阳离子进行传感

  摘要：

  摘要 基于 pytpy (pytpy = 4'-(4-pyridyl)-3,2':6',3″-terpyridine) 配体 [Cu(pytpy )(CN)]n(1)，已被溶剂热合成并表征。光致发光特性表明，1可以通过发光猝灭作为对硝基炸药和Fe3+的高灵敏度传感器。这项研究表明，1 可能是一种有用的金属离子和有机小分子发光传感器。

  DOI：

  10.1016/j.inoche.2016.09.012

文献信息

• A Zn(<scp>ii</scp>) coordination polymer and its photocycloaddition product: syntheses, structures, selective luminescence sensing of iron(<scp>iii</scp>) ions and selective absorption of dyes
  作者：Fei-long Hu、Yi-Xiang Shi、Huan-Huan Chen、Jian-Ping Lang

  DOI：10.1039/c5dt03094c

  日期：——

  polymer [Zn2(L)2(bpe)2(H2O)2] (1) (L = 4,4′-((1,2-phenylenebis(methylene))bis(oxy))dibenzoic acid; bpe = (E)-1,2-di(pyridin-4-yl)ethene) was prepared and structurally determined. Compound 1 has a chain structure in which its pair of bpe ligands is arranged in a head-to-tail manner with their CC bonds being close enough for a [2 + 2] cycloaddition reaction. Upon exposure to UV light, compound 1 undergoes

  一种配位聚合物[Zn 2（L）2（bpe）2（H 2 O）2 ]（1）（L = 4,4'-（（（1,2-亚苯基双（亚甲基））双（氧））二苯甲酸；制备bpe ＝（E）-1，2，2-二（吡啶-4-基）乙烯）并进行结构测定。化合物1具有链结构，其中其一对bpe配体以从头到尾的方式排列，其C C键足够紧密以进行[2 + 2]环加成反应。暴露于紫外线下，化合物1经历单晶至单晶（SCSC）[2 + 2]光二聚作用，从而生成一种2D配位聚合物[Zn（L）（rctt -tpcb）0.5（H 2 O）]（1a）（rctt（区域顺式，反式，反式）-tpcb ＝四（4-吡啶基）环丁烷）。1a晶体中的tpcb配体表现出令人着迷的原位热异构化。1的纳米球可通过在DMSO /酒精中重结晶而获得。1a的纳米球也可以通过光环二聚化方法从相应的1的纳米球中轻松生产。与1a的纳米球相比，1的纳米球显示出对Fe 3+的高度选择
• Construction of Entangled Coordination Polymers Based on M²⁺ Ions, 4,4′-{[1,2-Phenylenebis(methylene)]bis(oxy)}dibenzoate and Different N-Donor Ligands
  作者：Fei-Long Hu、Wei Wu、Peng Liang、Yun-Qiong Gu、Li-Gang Zhu、Han Wei、Jian-Ping Lang

  DOI：10.1021/cg401212s

  日期：2013.11.6

  Reactions of several transition metal [M = Mn(II), Cu(II), Zn(II), Co(II)] salts with 4,4′-[1,2-phenylenebis(methylene)]bis(oxy)}dibenzoic acid (H2L) and auxiliary N-donor ligands afforded a series of entangled coordination frameworks, [Mn2L2(4,4′-bpy)2][Mn2L2(H2O)2]·2H2O (1), [CuL(bbm)]·0.5H2O (2), [CuL(4,4′-bpy)0.5] (3), [Zn3L2(4,4′-bpy)2(HCOO)2] (4), [ZnL(4,4′-bpy)]2·H2O (5), [Co4L4(bpp)2]·DMF (6)

  几种过渡金属[M = Mn（II），Cu（II），Zn（II），Co（II）]盐与4,4'-[1,2-亚苯基双（亚甲基）]双（氧基）的反应}二苯甲酸（H 2 L）和辅助的N供体配体提供了一系列纠缠的配位骨架[Mn 2 L 2（4,4'-bpy）2 ] [Mn 2 L 2（H 2 O）2 ]· 2H 2 O （1），[CuL（bbm）]·0.5H 2 O （2），[CuL（4,4'-bpy）0.5 ] （3），[Zn 3 L 2（4,4'-bpy） ）2（HCOO）2 ] （4），[ZnL（4,4'-bpy）] 2 ·H 2 O （5），[Co 4 L 4（bpp）2 ]·DMF （6），[Co 2 L 2（bbm）] 2 ·2H 2 O （7）和[CoL（2,2'-bpy）] （8） [2,2'-bpy = 2,2'-联吡啶；4,4'-bpy = 4,4'-联吡啶; bbm = 1,4-二（1H-咪唑-1-基）苯;
• A series of transition metal coordination polymers with mixed ligands: Specific sensing and removal of metal ions
  作者：Jun Wang、Chuan-Ti Li、Chao Bai、Huai-Ming Hu、Gang-Lin Xue

  DOI：10.1016/j.ica.2017.07.005

  日期：2017.9

  Abstract Starting from the transition metal salts and mixed organic ligands of 4,4′-[1,2-phenylenebis-(methylene)]bis(oxy)}dibenzoic acid (H 2 L) and different N-containing linkers, six new coordination polymers, [Cd(L)(2,2′-bipy)] n ( 1 ); [Cu(L)(2,2′-bipy)] n ( 2 ); [Zn(L)(4,4′-bipy)][Zn(L)(H 2 O)]} n ( 3 ); [Cu(L)(4,4′-bipy) 0.5 (H 2 O)] n ( 4 ), [Zn 2 (L) 2 (bpp)] n ( 5 ) and [Cd 3 (L) 2 (OAc)

  摘要从4,4'-[1,2，亚苯基双（（亚甲基）]双（氧基）}二苯甲酸（H 2 L）和不同的含氮连接体的过渡金属盐和混合的有机配体开始，提出了六个新的配位聚合物，[Cd（L）（2,2'-bipy）] n（1）; [Cu（L）（2,2'-bipy）] n（2）; [Zn（L）（4,4'-bipy）] [Zn（L）（H 2 O）]} n（3）; [Cu（L）（4,4'-bipy）0.5（H 2 O）] n（4），[Zn 2（L）2（bpp）] n（5）和[Cd 3（L）2（OAc） ）2（Him）2] n（6）（2,2'-bipy = 2,2'-联吡啶，4,4'-bpy = 4,4'-联吡啶和bpp = 1,3-bis（4-合成并表征。1-6的结构差异表明辅助N-供体配体的作用，金属中心的性质可能会调节最终的结构。详细研究了1和5对Cu 2+阳离子和硝基炸药的光致发光行为。有趣的是，
• A family of entangled coordination polymers constructed from a flexible V-shaped long bicarboxylic acid and auxiliary N-donor ligands: Luminescent sensing
  作者：Jun Wang、Chao Bai、Huai-Ming Hu、Fei Yuan、Gang-Lin Xue

  DOI：10.1016/j.jssc.2017.02.015

  日期：2017.5

  4′-bipyrazole), have been hydrothermally synthesized and structurally characterized. 1–8 display various coordination motifs with different entangled forms and conformations due to the effect of the assistant N-donor ligands. The photoluminescent properties of compounds 1–8 in solid state were studied. Interestingly, 3 exhibits highly efficient luminescent sensing for Cu2+ cations and CrO42- anions, as well as

  摘要 8种Zn(II)基配位聚合物，即[Zn2L2(2,2'-bipy)]n·n (1)、[Zn2L2(phen)]n·n (2)、[ZnL(phen)( H2O)]n (3), [Zn3L3(4,4'-bipy)]n (4), [Zn2L2(4,4'-bipy)2]n [Zn2L2( )2]n·2n (5) , [Zn4L4(bpp)2]n (6), [ZnL(bbi)0.5]n (7), [ZnL(bpz)]n (8) (H2L=4,4'-[1,2-亚苯基双-(亚甲基)]双(氧基)}二苯甲酸，2,2'-bipy =2,2'-联吡啶，phen =1,10-菲咯啉，4,4'-bpy=4,4'-联吡啶，bpp =1,3-双(4-吡啶基)丙烷, bbi=1,4-双(咪唑-1-基)丁烷, bpz=3,3',5,5'-四甲基-4,4'-联吡唑) , 已被水热合成和结构表征。由于辅助
• Four new coordination complexes prepared for the degradation of methyl violent dye based on flexible dicarboxylate and different N-donor coligands
  作者：Lu Lu、Jun Wang、Chunyue Shi、Xiaodi Jiang、Yanchun Sun、Weiping Wu、Wuxin Hu

  DOI：10.1016/j.molstruc.2020.129181

  日期：2021.2

  acid, 4,4′-[1,2-phenylenebis-(methylene)]bis(oxy) dibenzoic acid (H2L), was used as highly versatile building block for the hydrothermal generation of a series of coordination polymeric architectures in thepresence of 1,1′-(1,4-butanediyl)bis(imidazole) (bbi) and 1,10-phenanthroline (phen). These were formulated as [Co2(L)2(bbi)·CH3CN]n (1), [Cu(L)(bbi)]n (2), [Co(L)(phen)(H2O)]n (3), and [Cu(L)(phen)(H2O)·2CH3CN]n

  摘要 醚桥联二羧酸 4,4'-[1,2-亚苯基双-(亚甲基)]双(氧基)二苯甲酸 (H2L)，被用作高度通用的构建块，用于一系列水热发电。在 1,1'-(1,4-丁二基)双(咪唑) (bbi) 和 1,10-菲咯啉 (phen) 存在下的配位聚合物结构。这些被公式化为 [Co2(L)2(bbi)·CH3CN]n (1), [Cu(L)(bbi)]n (2), [Co(L)(phen)(H2O)]n (3 ) 和 [Cu(L)(phen)( )·2CH3CN]n (4)，已被合成和表征。N-供体结构单元和金属离子的性质对结构多样性有显着影响。研究了所选材料的光催化性能，表明 2 是一种很有前途的光催化剂，用于紫外光驱动降解甲基紫 (MV) 作为模型有机染料污染物。