5-[(Z)-(4-hydrazinosulfonylbenzylidene)]-3-methyl-2,4-imidazolidinedione | 214466-46-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑烷类
• 英文名称: 5-[(Z)-(4-hydrazinosulfonylbenzylidene)]-3-methyl-2,4-imidazolidinedione
• 英文别名: 4-((1-Methyl-2,5-dioxo-4-imidazolidinylidene)methyl)benzenesulfonohydrazide；4-[(Z)-(1-methyl-2,5-dioxoimidazolidin-4-ylidene)methyl]benzenesulfonohydrazide
• CAS: 214466-46-3
• 化学式: C₁₁H₁₂N₄O₄S
• 分子量: 296.307
• InChiKey: FBPZAVUNFCTVMH-TWGQIWQCSA-N

物化性质

• 密度：
  1.525±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -0.5
• 重原子数：
  20
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.09
• 拓扑面积：
  130
• 氢给体数：
  3
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  D-吡喃木糖 、 5-[(Z)-(4-hydrazinosulfonylbenzylidene)]-3-methyl-2,4-imidazolidinedione 以 甲醇 为溶剂， 反应 6.0h， 以78%的产率得到4-[(Z)-(1-methyl-2,5-dioxoimidazolidin-4-ylidene)methyl]-N'-[(2R,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]benzenesulfonohydrazide
  参考文献：
  名称：

  Discussion

  摘要：

  A series of 5-[(Z)-(4-(2-(E)-arylidene)hydrazonosulfonylbenzylidene)]-2, 4-imidazolidinediones 6a-h and 5-[(Z)-(4-(2-beta-D-glycopyranosyl) hydrazinosulfonylbenzylidene)]-2,4-imidazolidinediones 10a-j were synthesized via two different routes. The compounds did not display any antiviral and antitumoral activity.

  DOI：

  10.1016/s0008-6215(98)00024-x
• 作为产物：
  描述：

  5-[(Z)-(4-chlorosulfonylbenzylidene)]-3-methyl-2,4-imidazolidinedione 在 一水合肼 作用下， 以 1,4-二氧六环 为溶剂， 以76%的产率得到5-[(Z)-(4-hydrazinosulfonylbenzylidene)]-3-methyl-2,4-imidazolidinedione
  参考文献：
  名称：

  Discussion

  摘要：

  A series of 5-[(Z)-(4-(2-(E)-arylidene)hydrazonosulfonylbenzylidene)]-2, 4-imidazolidinediones 6a-h and 5-[(Z)-(4-(2-beta-D-glycopyranosyl) hydrazinosulfonylbenzylidene)]-2,4-imidazolidinediones 10a-j were synthesized via two different routes. The compounds did not display any antiviral and antitumoral activity.

  DOI：

  10.1016/s0008-6215(98)00024-x

文献信息

• Discussion
  作者：Khodair, Ahmed I.

  DOI：10.1016/s0008-6215(98)00024-x

  日期：1998.1

  A series of 5-[(Z)-(4-(2-(E)-arylidene)hydrazonosulfonylbenzylidene)]-2, 4-imidazolidinediones 6a-h and 5-[(Z)-(4-(2-beta-D-glycopyranosyl) hydrazinosulfonylbenzylidene)]-2,4-imidazolidinediones 10a-j were synthesized via two different routes. The compounds did not display any antiviral and antitumoral activity.