3-(3-hydroxyprop-1-(t)-enyl)-7.beta.-(.alpha.-substituted acetamido)-ceph-3-em-4-carboxylic acids; 3-(3-carbamoyloxyprop-1-(t)-enyl)-7.beta.-(.alpha.-substituted acetamido)-ceph-3-em-4-carboxylic acids; and 3-[3-(N-substituted carbamoyloxy)prop-1-(t)-enyl]-7.beta.-(.alpha.-substituted acetamido)-ceph-3-em-4-carboxylic acids and derivatives and salts thereof and process for preparing such compounds. The compounds are useful as antibacterials and are active against a wide variety of gram positive and gram negative bacteria.
这段文字描述的是一种药物化合物,包括3-(3-羟基丙-1-(t)-烯基)-7.beta.-(.alpha.-取代乙酰胺基)-头孢-3-酮-4-
羧酸;3-(3-
氨基甲酰氧丙-1-(t)-烯基)-7.beta.-(.alpha.-取代乙酰胺基)-头孢-3-酮-4-
羧酸;以及3-[3-(N-取代
氨基甲酰氧)丙-1-(t)-烯基]-7.beta.-(.alpha.-取代乙酰胺基)-头孢-3-酮-4-
羧酸及其衍
生物和盐,并提供了制备这些化合物的方法。这些化合物可用作抗菌剂,对广泛的革兰氏阳性和革兰氏阴性细菌具有活性。