2-O-β-D-Glucopyranosyl-glycerol

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 甘油脂
• 英文名称: 2-O-β-D-Glucopyranosyl-glycerol
• 英文别名: 2-O-glucopyranosyl-glycerol；(3R,4S,5S,6R)-2-(1,3-dihydroxypropan-2-yloxy)-6-(hydroxymethyl)oxane-3,4,5-triol
• 化学式: C₉H₁₈O₈
• 分子量: 254.237
• InChiKey: AQTKXCPRNZDOJU-LOFWALOHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.5
• 重原子数：
  17
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  140
• 氢给体数：
  6
• 氢受体数：
  8

反应信息

• 作为产物：
  描述：

  甘油 、 对氟苯甲醇 在 Leuconostoc mesenteroides sucrose phosphorylase 作用下， 反应 0.17h， 生成 2-O-β-D-Glucopyranosyl-glycerol
  参考文献：
  名称：

  Small-molecule glucosylation by sucrose phosphorylase: structure–activity relationships for acceptor substrates revisited

  摘要：

  Sucrose phosphorylase catalyzes the O-glucosylation of a wide range of acceptor substrates. Acceptors presenting a suitable 1,2-diol moiety are glucosylated exclusively at the secondary hydroxyl. Production of the naturally occurring compatible solute, 2-O-alpha-D-glucopyranosyl-sn-glycerol, from sucrose and glycerol is a notable industrial realization of the regio- and stereoselective biotransformation promoted by sucrose phosphorylase. The acceptor substrate specificity of sucrose phosphorylase was analyzed on the basis of recent high-resolution crystal structures of the enzyme. Interactions at the acceptor binding site, observed in the crystal (D-fructosyl) and suggested by results of docking experiments (glycerol), are used to rationalize experimentally determined efficiencies and regioselectivities of enzymatic glucosyl transfer. (c) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.carres.2010.03.035

文献信息

• METHOD FOR STABILIZING SCENT COMPONENT, FRAGRANCE COMPOSITION, AND DEODORIZING COMPOSITION
  申请人：Toyo Sugar Refining Co., Ltd.

  公开号：EP3040406A1

  公开（公告）日：2016-07-06

  It is an object of the present invention to provide a method for preventing deterioration (oxidation, decomposition or the like) of various smell components, e.g., fragrance components such as perfumes or odor-causing components such as unsaturated fatty acids; and a perfume composition in which deterioration of a perfume has been prevented (a stabilized perfume composition) and a deodorant composition capable of preventing deterioration of an unsaturated fatty acid. The method for preventing deterioration of a smell component according to the present invention is characterized by allowing D-glucopyranosylglycerol to coexist with a smell component. Examples of the smell components include perfumes and unsaturated fatty acids. The perfume composition of the present invention is characterized by containing at least one perfume and D-glucopyranosylglycerol as an active ingredient for preventing deterioration of the perfume. The deodorant composition of the present invention is characterized by containing D-glucopyranosylglycerol as an active ingredient for preventing deterioration of an unsaturated fatty acid.

  本发明的目的是提供一种防止各种气味成分（例如香水等香味成分或不饱和脂肪酸等致臭成分）变质（氧化、分解或类似物）的方法；以及一种防止香水变质的香水组合物（稳定香水组合物）和一种能够防止不饱和脂肪酸变质的除臭组合物。根据本发明，防止香味成分变质的方法的特点是允许 D-吡喃葡萄糖基甘油与香味成分共存。气味成分的例子包括香水和不饱和脂肪酸。本发明香水组合物的特点是含有至少一种香水和作为防止香水变质的活性成分的 D-吡喃葡萄糖基甘油。本发明除臭剂组合物的特点是含有 D-吡喃葡萄糖基甘油作为防止不饱和脂肪酸变质的活性成分。
• Processes and host cells for genome, pathway, and biomolecular engineering
  申请人：enEvolv, Inc.

  公开号：US10370654B2

  公开（公告）日：2019-08-06

  The present disclosure provides compositions and methods for genomic engineering.

  本公开提供了基因组工程的组合物和方法。
• PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING
  申请人：ENEVOLV, INC.

  公开号：US20160186168A1

  公开（公告）日：2016-06-30

  The present disclosure provides compositions and methods for genomic engineering.
• US9944925B2
  申请人：——

  公开号：US9944925B2

  公开（公告）日：2018-04-17