2-Hydroximino-3-methyl-pentansaeure-(1) | 69946-40-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2-Hydroximino-3-methyl-pentansaeure-(1)
• 英文别名: 3-Methyl-2-oxo-valeriansaeure-oxim；N-hydroxy-2-imino-3-methylpentanoic acid；2-hydroxyimino-3-methyl-valeric acid；2-Hydroxyimino-3-methyl-valeriansaeure；2-(Hydroxyimino)-3-methylpentanoic acid；2-hydroxyimino-3-methylpentanoic acid
• CAS: 69946-40-3
• 化学式: C₆H₁₁NO₃
• mdl: MFCD19228444
• 分子量: 145.158
• InChiKey: DVMVJFPPLQFMJY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  10
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.666
• 拓扑面积：
  69.9
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  2-Hydroximino-3-methyl-pentansaeure-(1) 在 sodium cyanoborohydride 、 溶剂黄146 、 盐酸 作用下， 以 水 为溶剂， 反应 3.0h， 以83%的产率得到N-hydroxy-2-amino-3-methyl-pentanoic acid
  参考文献：
  名称：

  Evaluation of hadacidin analogues

  摘要：

  Several derivatives of hadacidin have been developed and evaluated for activity against adenylosuccinate synthetase. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2010.10.088
• 作为产物：
  描述：

  3-甲基-2-氧基戊酸 在 盐酸羟胺 、 sodium hydroxide 作用下， 以 水 为溶剂， 以67%的产率得到2-Hydroximino-3-methyl-pentansaeure-(1)
  参考文献：
  名称：

  Evaluation of hadacidin analogues

  摘要：

  Several derivatives of hadacidin have been developed and evaluated for activity against adenylosuccinate synthetase. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2010.10.088

文献信息

• Hamlin; Hartung, Journal of Biological Chemistry, 1942, vol. 145, p. 352
  作者：Hamlin、Hartung

  DOI：——

  日期：——
• Locquin, Bulletin de la Societe Chimique de France, 1906, vol. <3> 35, p. 964
  作者：Locquin

  DOI：——

  日期：——
• Bouveault; Locquin, Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1905, vol. 141, p. 116
  作者：Bouveault、Locquin

  DOI：——

  日期：——
• Inui; Kaneko, Nippon Kagaku Zasshi, 1956, vol. 77, p. 1623
  作者：Inui、Kaneko

  DOI：——

  日期：——
• Hydrotreating and/or hydrocracking catalyst of hydrocarbons and preparation thereof
  申请人：Cholley Thierry

  公开号：US20070114155A1

  公开（公告）日：2007-05-24

  The invention relates to a hydroconversion catalyst, which comprises a refractory oxide support, at least one metal selected from group VIII and at least one metal selected from group VIB and which is characterized in that it has at least one organic compound containing at least one oxime group of formula (I)>C═NOR 1 , in which R 1 is selected among hydrogen and alkyl, allyl, aryl, alkylene or cycloaliphatic groups, and combinations thereof, these groups being able to be substituted by at least one electron donor group.