N-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)-hydroperoxyphosphonamidic acid

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: N-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)-hydroperoxyphosphonamidic acid
• 化学式: C₁₁H₁₄N₃O₅P
• 分子量: 299.22
• InChiKey: SVGZEZSRLQZYLT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.8
• 重原子数：
  20
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  102
• 氢给体数：
  3
• 氢受体数：
  7

文献信息

• Multiple-enzyme nanocomplexes
  申请人：Lu Yunfeng

  公开号：US10016490B2

  公开（公告）日：2018-07-10

  Provided are nanocomplexes having at least two different enzymes and a polymeric network anchored to at least one of the enzymes. In some embodiments, the activities of the enzymes catalyze a cascade reaction.

  本文提供的纳米复合物具有至少两种不同的酶和锚定在至少一种酶上的聚合物网络。在某些实施方案中，酶的活性可催化级联反应。
• MULTIPLE-ENZYME NANOCOMPLEXES
  申请人：Lu Yunfeng

  公开号：US20140134700A1

  公开（公告）日：2014-05-15

  Provided are nanocomplexes having at least two different enzymes and a polymeric network anchored to at least one of the enzymes. In some embodiments, the activities of the enzymes catalyze a cascade reaction.
• ORAL DELIVERY OF ENZYMES BY NANOCAPSULES FOR TARGETED METABOLISM OF ALCOHOL OR TOXIC METABOLITES
  申请人：Yang Otto O.

  公开号：US20140186436A1

  公开（公告）日：2014-07-03

  The invention disclosed herein includes nanocomplexes that are designed include enzymes that have complementary functional attributes and methods for using these nanocomplexes. Illustrative examples include nanocomplexes that comprise both an alcohol oxidase enzyme as well as a catalase enzyme. These nanocomplexes can be used in methods designed to lower blood alcohol levels in vivo, and/or to break down the toxic byproducts of alcohol metabolism. Consequently these nanocomplexes can be used to treat a variety of conditions resulting from the consumption of alcohol, including for example, acute alcohol intoxication.