7-(Hydroxymethyl)-3,5-dimethoxy-2-(4-methoxy-3-methylphenyl)chromen-4-one

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: 7-(Hydroxymethyl)-3,5-dimethoxy-2-(4-methoxy-3-methylphenyl)chromen-4-one
• 英文别名: 7-(hydroxymethyl)-3,5-dimethoxy-2-(4-methoxy-3-methylphenyl)chromen-4-one
• 化学式: C₂₀H₂₀O₆
• 分子量: 356.4
• InChiKey: CMYPMZPRNGINHN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  26
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  74.2
• 氢给体数：
  1
• 氢受体数：
  6

文献信息

• NOVEL USE OF FLAVONE-BASED COMPOUND
  申请人：Industry-Academic Cooperation Foundation, Younsei University

  公开号：US20140148504A1

  公开（公告）日：2014-05-29

  The present invention relates to a novel use of a flavone-based compound or a Kaempferia parviflora extract comprising the same. More particularly, the present invention relates to a composition for wrinkle improvement, anti-aging and skin elasticity enhancement or a composition for skin moisturization, which comprises a flavone-based compound or a Kaempferia parviflora extract comprising the same as an active ingredient. The composition of the present invention is very effective in inhibiting the activity of Collagenase-1 (MMP-1) and promoting the synthesis of collagen. Therefore, the composition of the present invention is useful for wrinkle improvement, anti-aging, skin elasticity enhancement, and skin moisturization via the inhibition of moisture loss from the skin.