5-Iodo-3,4,5-triazatetracyclo[13.4.0.02,6.07,12]nonadeca-1(19),2(6),3,7,9,11,15,17-octaene

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 5-Iodo-3,4,5-triazatetracyclo[13.4.0.02,6.07,12]nonadeca-1(19),2(6),3,7,9,11,15,17-octaene
• 英文别名: 5-iodo-3,4,5-triazatetracyclo[13.4.0.02,6.07,12]nonadeca-1(19),2(6),3,7,9,11,15,17-octaene
• 化学式: C₁₆H₁₂IN₃
• 分子量: 373.19
• InChiKey: KRWWLOHWAGMCTK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  20
• 可旋转键数：
  0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  30.7
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• Modified polyaryletherketone polymer (PAEK) and process to obtain it
  申请人：Universidad Del Pais Vasco-Euskal Herriko Unibertsitatea

  公开号：EP2749300A1

  公开（公告）日：2014-07-02

  The present invention relates to a modified polyaryletherketone polymer (PAEK) with chemically modified surfaces with azides, alkynes, thiols, maleimides, sulfonylazides or thio acids, suitable for "click" reactions and to a process to obtain it. It also relates to the conjugated biomaterials derived thereof, PAEK type materials with surfaces modified with a RGD (Arg- Gly-Asp) and/or OGP10-14 (Tyr-Gly-Phe-Gly-Gly) peptidomimetics and to a process to obtain it. These materials are particularly useful for manufacturing medical devices. Finally, the present invention also relates to a fluorescent PAEK material.

  本发明涉及一种改性聚芳醚酮聚合物（PAEK），其表面经叠氮化物、炔烃、硫醇、马来酰亚胺、磺酰基氮化物或硫代酸化学改性，适用于 "点击 "反应，还涉及一种获得该聚合物的工艺。它还涉及由其衍生的共轭生物材料，即表面用 RGD（Arg-Gly-Asp）和/或 OGP10-14（Tyr-Gly-Phe-Gly-Gly）拟肽修饰的 PAEK 型材料，以及获得这种材料的工艺。这些材料特别适用于制造医疗器械。最后，本发明还涉及一种荧光 PAEK 材料。
• NOVEL CROSSLINKED ALGINIC ACID
  申请人：Mochida Pharmaceutical Co., Ltd.

  公开号：EP3808783A1

  公开（公告）日：2021-04-21

  The present invention provides alginic acid derivatives represented by formula (I) and formula (II), and a novel crosslinked alginic acid obtained by carrying out a Huisgen reaction using an alginic acid derivative of formula (I) and an alginic acid derivative of formula (II). There are thereby provided novel alginic acid derivatives and a novel crosslinked alginic acid.

  本发明提供了由式（I）和式（II）表示的海藻酸衍生物，以及通过使用式（I）的海藻酸衍生物和式（II）的海藻酸衍生物进行惠斯根反应而获得的新型交联海藻酸。由此提供了新型海藻酸衍生物和新型交联海藻酸。