1-[2,6-Dichloro-4-(trifluoromethyl)phenyl]-4-ethylsulfinyl-5-(fluoromethyl)pyrazole-3-carbonitrile

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 1-[2,6-Dichloro-4-(trifluoromethyl)phenyl]-4-ethylsulfinyl-5-(fluoromethyl)pyrazole-3-carbonitrile
• 英文别名: 1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-ethylsulfinyl-5-(fluoromethyl)pyrazole-3-carbonitrile
• 化学式: C₁₄H₉Cl₂F₄N₃OS
• 分子量: 414.2
• InChiKey: BZOBAHBAOUNKQF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  25
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  77.9
• 氢给体数：
  0
• 氢受体数：
  8

文献信息

• 1-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF
  申请人：AVENTIS AGRICULTURE

  公开号：US20150133506A1

  公开（公告）日：2015-05-14

  Provided are 1-aryl-5-alkyl pyrazole compounds, of formula (I): wherein: R 1 is hydrogen, cyano, halogen, R 8 , formyl, —C(O)R 8 , —C(O)OR 8 , —C(O)NR 9 R 10 , or —C(S)NH 2 ; R 2 is R 8 or —S(O) m R 11 ; R 3 is methyl, ethyl or C 1 -C 4 haloalkyl; R 4 , R 5 and R 7 are independently hydrogen, halogen, alkyl, haloalkyl, cyano or nitro; R 6 is halogen, alkyl, haloalkyl, alkoxy, haloalkyloxy, cyano, nitro, —C(O)R 12 , —S(O) n R 12 or SF 5 ; Z is a nitrogen atom or C—R 13 ; R 8 is alkyl, haloalkyl, cycloalkyl or halocycloalkyl; R 9 is hydrogen, alkyl, haloalkyl or alkoxy; R 10 is hydrogen, alkyl, haloalkyl or alkoxy; R 11 is alkyl, haloalkyl, alkenyl, haloalkenyl, alkynyl, haloalkynyl or cycloalkyl; R 12 is alkyl or haloalkyl; R 13 is hydrogen, halogen, cyano, nitro, alkyl, haloalkyl, alkoxy or haloalkoxy; m is 0, 1 or 2; and n is 0, 1 or 2; or a salt thereof, the method of making compounds of formula (I) and the use of these compounds against ectoparasites, endoparasites and pests.

  提供了1-芳基-5-烷基吡唑化合物，化学式如下（I）：其中：R1为氢、氰、卤素、R8、甲酰基、—C（O）R8、—C（O）OR8、—C（O）NR9R10或—C（S）NH2；R2为R8或—S（O）mR11；R3为甲基、乙基或C1-C4卤代烷基；R4、R5和R7独立地为氢、卤素、烷基、卤代烷基、氰或硝基；R6为卤素、烷基、卤代烷基、烷氧基、卤代烷氧基、氰、硝基、—C（O）R12、—S（O）nR12或SF5；Z为氮原子或C—R13；R8为烷基、卤代烷基、环烷基或卤代环烷基；R9为氢、烷基、卤代烷基或烷氧基；R10为氢、烷基、卤代烷基或烷氧基；R11为烷基、卤代烷基、烯基、卤代烯基、炔基、卤代炔基或环烷基；R12为烷基或卤代烷基；R13为氢、卤素、氰、硝基、烷基、卤代烷基、烷氧基或卤代烷氧基；m为0、1或2；n为0、1或2；或其盐，制备化合物（I）的方法以及这些化合物对外寄生虫、内寄生虫和害虫的用途。
• US8785372B2
  申请人：——

  公开号：US8785372B2

  公开（公告）日：2014-07-22
• US9339033B2
  申请人：——

  公开号：US9339033B2

  公开（公告）日：2016-05-17