Aryl and heteroaryl compounds and methods to modulate coagulation
申请人:——
公开号:US20040110832A1
公开(公告)日:2004-06-10
This invention provides certain compounds, methods of their preparation, pharmaceutical compositions comprising the compounds, and their use in treating human or animal disorders. The compounds of the invention are useful as antagonists, or more preferably, partial antagonist of factor IX and thus, may be used to inhibit the intrinsic pathway of blood coagulation. The compounds are useful in a variety of applications including the management, treatment and/or control of diseases caused in part by the intrinsic clotting pathway utilizing factor IX. Such diseases or disease states include stroke, myocardial infarction, aneurysm surgery, and deep vein thrombosis associated with surgical procedures, long periods of confinement, and acquired or inherited pro-coagulant states.
ARYL AND HETEROARYL COMPOUNDS AND METHODS TO MODULATE COAGULATION
申请人:TransTech Pharma Inc.
公开号:EP1546089A2
公开(公告)日:2005-06-29
US7122580B2
申请人:——
公开号:US7122580B2
公开(公告)日:2006-10-17
[EN] ARYL AND HETEROARYL COMPOUNDS AND METHODS TO MODULATE COAGULATION<br/>[FR] COMPOSES ARYLE ET HETEROARYLE ET PROCEDES DE MODULATION DE LA COAGULATION