5-[4-(trifluoromethoxy)phenyl]-1H-1,2,4-triazole

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 5-[4-(trifluoromethoxy)phenyl]-1H-1,2,4-triazole
• 化学式: C₉H₆F₃N₃O
• 分子量: 229.16
• InChiKey: LXQOVFZDUJUAPG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  50.8
• 氢给体数：
  1
• 氢受体数：
  6

文献信息

• [EN] IMPROVED PROCESS FOR THE PREPARATION OF CERTAIN TRIARYL RHAMNOSE CARBAMATES<br/>[FR] PROCÉDÉ AMÉLIORÉ POUR LA PRÉPARATION DE CERTAINS TRIARYL-RHAMNOSE CARBAMATES
  申请人：DOW AGROSCIENCES LLC

  公开号：WO2014158646A1

  公开（公告）日：2014-10-02

  Aryl or heteroaryl 1-substituted triazoles are prepared from 3-bromo-1H-1,2,4-triazole by reaction with a brominated or iodinated aryl or heteroaryl group.
• [EN] PREPARATION OF TRIARYL RHAMNOSE CARBAMATES<br/>[FR] PRÉPARATION DE TRIARYLE-RHAMNOSE CARBAMATES
  申请人：DOW AGROSCIENCES LLC

  公开号：WO2014158647A1

  公开（公告）日：2014-10-02

  Aryl boronic esters containing the rhamnose carbamate moiety are prepared in good yield and without cleavage of the carbamate linkage by first contacting p-bromophenyl isocyanate with a tetrahydropyran-2-ol followed by reaction with a diboron compound.
• [EN] PROCESS FOR THE PREPARATION OF TRIARYL RHAMNOSE CARBAMATES<br/>[FR] PROCÉDÉ DE PRÉPARATION DE TRIARYL-RHAMNOSE CARBAMATES
  申请人：DOW AGROSCIENCES LLC

  公开号：WO2014186027A1

  公开（公告）日：2014-11-20

  Aryl or heteroaryl 1-substituted triazoles are prepared by cyclizing aryl or heteroaryl hydrazines with urea and alkyl orthoformates.