2-morpholino-4-(4-methoxyphenyl)thiazole | 256661-25-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 2-morpholino-4-(4-methoxyphenyl)thiazole
• 英文别名: 4-[4-(4-Methoxyphenyl)-1,3-thiazol-2-yl]morpholine
• CAS: 256661-25-3
• 化学式: C₁₄H₁₆N₂O₂S
• 分子量: 276.359
• InChiKey: TZNJZGDNHCDDPK-UHFFFAOYSA-N

物化性质

• 沸点：
  453.5±55.0 °C(Predicted)
• 密度：
  1.229±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  19
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  62.8
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  2-morpholino-4-(4-methoxyphenyl)thiazole 在 哌啶 、 三氯氧磷 作用下， 以 甲醇 为溶剂， 反应 2.0h， 生成 2-[4-(4-Methoxy-phenyl)-2-morpholin-4-yl-thiazol-5-ylmethylene]-malononitrile
  参考文献：
  名称：

  SYNTHESIS AND SOLVATOCHROMIC PROPERTIES OF 5-DICYANOVINYL-AND 5-TRICYANOVINYL-SUBSTITUTED 2-AMINO-THIAZOLES AND 2-AMINO-THIOPHENES

  摘要：

  Starring from 2-morpholinothiazoles 6 and 2-morpholinothiophenes 7 and following known routes several 5-dicyanovinyl and 5-tricyanovinyl-substituted derivatives 10 - 13 have been prepared and their solvatochromic properties estimated.

  DOI：

  10.1080/10426509908031622
• 作为产物：
  描述：

  alpha-溴-4-甲氧基苯乙酮 在 溶剂黄146 作用下， 以 乙醇 、 丙酮 为溶剂， 反应 2.0h， 生成 2-morpholino-4-(4-methoxyphenyl)thiazole
  参考文献：
  名称：

  SYNTHESIS AND SOLVATOCHROMIC PROPERTIES OF 5-DICYANOVINYL-AND 5-TRICYANOVINYL-SUBSTITUTED 2-AMINO-THIAZOLES AND 2-AMINO-THIOPHENES

  摘要：

  Starring from 2-morpholinothiazoles 6 and 2-morpholinothiophenes 7 and following known routes several 5-dicyanovinyl and 5-tricyanovinyl-substituted derivatives 10 - 13 have been prepared and their solvatochromic properties estimated.

  DOI：

  10.1080/10426509908031622

文献信息

• COMPOSITION FOR DYEING KERATIN FIBRES, COMPRISING AN OXIDATION BASE AND A PARTICULAR HETEROARYL COUPLER
  申请人：L'OREAL

  公开号：US20170087075A1

  公开（公告）日：2017-03-30

  The invention relates to a composition comprising: i) at least one oxidation base, preferably of heterocyclic and/or para-phenylenediamine type; and ii) at least one heteroaryl coupler of formula (I), with R 1 , R 2 , R 3 , A and X as defined in the description. The invention also relates to a process for dyeing keratin fibres using ingredients i) and ii); to a kit comprising ingredients i) and ii); and to the use of ingredient i) combined with ii) for dyeing keratin fibres. The composition of the invention leads to particularly powerful, chromatic and sparingly selective colourings.
• US9993409B2
  申请人：——

  公开号：US9993409B2

  公开（公告）日：2018-06-12