4,6-di(p-chlorocinnamoyl)resorcinol | 115540-50-6

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 直链 1,3-二芳基丙烷
• 英文名称: 4,6-di(p-chlorocinnamoyl)resorcinol
• 英文别名: (E)-3-(4-chlorophenyl)-1-[5-[(E)-3-(4-chlorophenyl)prop-2-enoyl]-2,4-dihydroxyphenyl]prop-2-en-1-one
• CAS: 115540-50-6
• 化学式: C₂₄H₁₆Cl₂O₄
• 分子量: 439.295
• InChiKey: BLDGKMNEEVXTHU-YDWXAUTNSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.1
• 重原子数：
  30
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  74.6
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  4,6-di(p-chlorocinnamoyl)resorcinol 在 sodium hydroxide 、 双氧水 作用下， 以 乙醇 为溶剂， 以41%的产率得到2,8-di-(p-chlorophenyl)-3,7-dihydroxy-4,6-dioxo-4H,6H-benzo<1,2-b:5,4-b'>dipyran
  参考文献：
  名称：

  Ashok, D.; Sarma, P. N., Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1987, vol. 26, # 1-12, p. 900 - 902

  摘要：

  DOI：
• 作为产物：
  描述：

  1,1'-(4,6-二羟基苯)二乙酮 生成 4,6-di(p-chlorocinnamoyl)resorcinol
  参考文献：
  名称：

  ASHOK, D.;SARMA, P. N, INDIAN J. CHEM., 26,(1987) N 9, 900-902

  摘要：

  DOI：

文献信息

• Reddy; Ashok; Sarma, Journal of the Indian Chemical Society, 1991, vol. 68, # 4, p. 242 - 243
  作者：Reddy、Ashok、Sarma

  DOI：——

  日期：——
• Reddy, R Jayasimha; Ashok, D; Sarma, P N, Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1993, vol. 32, # 3, p. 404 - 406
  作者：Reddy, R Jayasimha、Ashok, D、Sarma, P N

  DOI：——

  日期：——
• A Facile Synthesis of 3,7-Diphenyl-4,6-Distyryl-2,8-Dioxo-2H,8H-Benzo[1,2-b:5,4-b′]dipyrans and Their Antifeedant Activity
  作者：B. Sreenivasulu、P. N. Sarma

  DOI：10.1080/00397919708003383

  日期：1997.7

  The synthesis, characterisation and antifeedant activity of some new dicoumarins prepared from 4,6-diacetyl resorcinol has been reported.
• Microwave assisted selective synthesis of (E)-1-(4-Chloro-7-hydroxy-2-aryl-2H-chromen-6-yl)-3-arylprop-2-en-1-ones and their antimicrobial activity
  作者：D. Ashok、M. Sarasija、D. Shravani、B. Vijayalaxmi、K. Sudershan

  DOI：10.1134/s1070363216040290

  日期：2016.4

  A series of new (E)-1-(4-chloro-7-hydroxy-2-aryl-2H-chromen-6-yl)-3-arylprop-2-en-1-ones (2a-2f) have been synthesized by selective mono cyclization of 4,6-dicinnamoyl resorcinols (1a-1f) using Vilsmeier-Haack reagent under conventional heating and microwave irradiation. The structures of the synthesized compounds have been elucidated by elemental analysis, IR, H-1 NMR, C-13 NMR and Mass spectral data. The synthesized compounds were tested in vitro for antimicrobial activity.
• Reddy, S. Purushotham; Sreenivasulu, B.; Sarma, P. N., Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1995, vol. 34, # 7, p. 658 - 659
  作者：Reddy, S. Purushotham、Sreenivasulu, B.、Sarma, P. N.

  DOI：——

  日期：——