2-<(thioethyl)amino>acetic acid | 3724-83-2

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2-<(thioethyl)amino>acetic acid
• 英文别名: N-(2-Mercaptoethyl)glycin；carboxymethyl cysteamine；Glycine, N-(2-mercaptoethyl)-；2-(2-sulfanylethylamino)acetic acid
• CAS: 3724-83-2
• 化学式: C₄H₉NO₂S
• mdl: MFCD19217820
• 分子量: 135.187
• InChiKey: IAICFWDJMWEXAO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.6
• 重原子数：
  8
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  50.3
• 氢给体数：
  3
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  氰胺 、 2-<(thioethyl)amino>acetic acid 在 ammonium hydroxide 作用下， 生成 N-Amidino-N-(2-thioethyl)glycin
  参考文献：
  名称：

  关于肌酸激酶的特异性。与肌酸相关的新糖氰胺和糖胺类似物。

  摘要：

  DOI：

  10.1021/ja00750a038
• 作为产物：
  描述：

  mercaptoethylglycine ethyl ester 在 盐酸 作用下， 生成 2-<(thioethyl)amino>acetic acid
  参考文献：
  名称：

  Bulavin,L.G., Journal of Organic Chemistry USSR (English Translation), 1971, vol. 7, p. 2168 - 2174

  摘要：

  DOI：

文献信息

• COMPOSITION AND METHOD FOR BINDING ACETALDEHYDE IN STOMACH
  申请人：Suovaniemi Osmo

  公开号：US20090253793A1

  公开（公告）日：2009-10-08

  This invention relates to a non-toxic composition which bind acetaldehyde present in the stomach, intestine and/or colon. The composition comprises one or more acetaldehyde-binding compound(s) comprising one or more free sulphhydryl and/or amino groups. The compound(s) are mixed with a non-toxic carrier that effects sustained release of said compound(s) in the gastrointestinal tract. These compositions are of benefit in particular to patients having atrophic gastritis or achlorhydric or low acid stomach.

  本发明涉及一种非毒性组合物，其能够结合存在于胃、肠和/或结肠中的乙醛。该组合物包括一种或多种含有一种或多种自由硫醇和/或氨基基团的乙醛结合化合物。这些化合物与一种非毒性载体混合，该载体在胃肠道中产生持续释放的作用。这些组合物对于患有萎缩性胃炎、无酸或低酸胃的患者尤其有益。
• FOOD COMPOSITION FOR BINDING ACETALDEHYDE IN MOUTH AND IN DIGESTIVE TRACK, AND METHOD FOR THE PREPARATION OF THE COMPOSITION
  申请人：SUOVANIEMI Osmo

  公开号：US20100063149A1

  公开（公告）日：2010-03-11

  The object of the invention comprises food compositions, to which one or more acetaldehyde-binding compounds are added. The purpose of the compositions is to reduce the amount of detrimental acetaldehyde in the area of the mouth, the pharynx, the oesophagus, the stomach, and the small and large intestines, and through this, to reduce the risk of developing cancers in these areas.

  本发明的对象包括添加了一种或多种乙醛结合化合物的食品组成物。这些组成物的目的是减少口腔、咽喉、食管、胃、小肠和大肠等区域中有害的乙醛含量，并通过这种方式减少这些区域发生癌症的风险。
• FILTER FOR A TOBACCO PRODUCT
  申请人：Salaspuro Ville

  公开号：US20100206318A1

  公开（公告）日：2010-08-19

  The invention relates to a cigarette holder-type component, which is intended to be attached to a tobacco product and can be adapted to the suction head of the tobacco product so that the smoke travels through the component during smoking. The component contains porous material, into which an aqueous solution containing at least one aldehyde-binding compound has been absorbed to form an aldehyde-binding filter. In the component that is to be attached to the tobacco product, the water content of the material is kept at a level where the aldehyde-binding compounds are capable of reacting with the aldehydes in the smoke, changing them into a harmless form.

  本发明涉及一种烟嘴式组件，旨在附着于烟草制品上，并可适应烟草制品的吸入口，使烟雾在吸烟过程中通过该组件。该组件包含多孔材料，其中吸收了至少一种醛类结合化合物的水溶液，形成醛类结合过滤器。在要附着于烟草制品上的组件中，保持材料的含水量在一定水平，使醛类结合化合物能够与烟雾中的醛类反应，将其转化为无害形式。
• COMPOSITION FOR FOODSTUFF FOR BINDING ACETALDEHYDE
  申请人：Suovaniemi Osmo

  公开号：US20100239663A1

  公开（公告）日：2010-09-23

  This invention relates to a non-toxic composition which bind acetaldehyde present in the stomach, intestine and/or colon. The composition comprises one or more acetaldehyde-binding compound(s) comprising one or more free sulphhydryl and/or amino groups. The compound(s) are mixed with a non-toxic carrier that effects sustained release of said compound(s) in the gastrointestinal tract. This invention relates also to food additives and food compositions and packages comprising the composition.

  本发明涉及一种非毒性化合物，用于捕捉胃、肠和/或结肠中存在的乙醛。该化合物包括一个或多个含有一个或多个自由硫醇和/或氨基基团的乙醛结合化合物。该化合物与一种非毒性载体混合，以在胃肠道中实现该化合物的持续释放。本发明还涉及包含该化合物的食品添加剂、食品组合物和包装。
• CHIOTELLIS, E.;STASSINOPOULOU, C. I.;VARVARIGOU, A.;VAVOURAKI, H., J. MED. CHEM., 1982, 25, N 11, 1370-1374
  作者：CHIOTELLIS, E.、STASSINOPOULOU, C. I.、VARVARIGOU, A.、VAVOURAKI, H.

  DOI：——

  日期：——