Acetic acid, nitrilotri-, disodium salt

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: Acetic acid, nitrilotri-, disodium salt
• 英文别名: disodium;2-[carboxylatomethyl(carboxymethyl)amino]acetate
• 化学式: C6H7NNa2O6
• 分子量: 235.1
• InChiKey: RHPXYIKALIRNFA-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  -10.12
• 重原子数：
  15
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  121
• 氢给体数：
  1
• 氢受体数：
  7

ADMET

毒理性

• 副作用

国际癌症研究机构致癌物-第3类：化学品无法被国际癌症研究机构分类。

IARC Carcinogen - Class 3: Chemicals are not classifiable by the International Agency for Research on Cancer.

来源:Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

反应信息

• 作为反应物：
  描述：

  三氯化铁 、 Acetic acid, nitrilotri-, disodium salt 生成 铁次氮基三乙酸盐
  参考文献：
  名称：

  SADA, EIZO;KUMAZAWA, HIDEHIRO;MACHIDA, HIROSHI, IND. AND ENG. CHEM. RES., 26,(1987) N 10, 2016-2019

  摘要：

  DOI：
• 作为产物：
  描述：

  Acetic acid, nitrilotri-, trisodium salt 、 硫酸 生成 Acetic acid, nitrilotri-, disodium salt
  参考文献：
  名称：

  Process for producing granular alkali metal nitrilotriacetate

  摘要：

  本发明揭示了一种制备高吸收性颗粒状碱金属NTA的方法，即通过将NTA粉末与部分中和量的酸接触。通过将碱金属NTA与酸接触，混合材料以制成颗粒，并然后干燥颗粒，从而产生大多数颗粒重量在-12至+80目尺寸范围内，密度至少约为0.70 g / cc，吸收性在吸收性测试范围内大于12 ml / 100 g的颗粒产品。酸可以分为一步或两步添加。在一步实施方式中，酸添加时间/混合时间比关键，而在两步添加实施方式中，混合时间不关键。但是，在两步实施方式中，首先将粉末与稀酸接触，第二个接触步骤是与浓酸接触。产生的颗粒产品具有密度至少约为0.70 g / cc，少于15％的细颗粒，吸收性在约12-14 ml / 100 g的范围内。

  公开号：

  US05861531A1

文献信息

• [EN] PURIFICATION PROCESS<br/>[FR] PROCÉDÉ DE PURIFICATION
  申请人：DOW TECHNOLOGY INVESTMENTS LLC

  公开号：WO2013048701A1

  公开（公告）日：2013-04-04

  A process for reducing the level of contaminant metals in ligands used in the preparation of catalysts is disclosed.

  本发明揭示了一种用于降低催化剂制备中所使用的配体中污染金属水平的过程。
• Process for the preparation of alkylene glycols
  申请人：Ledford S. John

  公开号：US20060122437A1

  公开（公告）日：2006-06-08

  Disclosed is a process for the preparation of alkylene glycols from the corresponding alkylene oxide, such as ethylene glycol from ethylene oxide, in the presence of water, a catalyst and, optionally, carbon dioxide. The catalyst contains an amphoteric compound, such as such as (ethylenedinitrilo) tetraacetic acid (EDTA). These befunctional compounds have both acid and base moieties. Preferably, a compound useful in the present invention forms a buffered solution in water, i.e., the acid and base moieties do not completely disassociate. The pH of the buffered solution should be 2-10, preferably 5-10, more preferably 4-9. A compound useful in the present invention is preferably organic with the base moiety and the acid moiety being separated by one to four carbon atoms.

  本发明揭示了一种从相应的环氧烷制备烷基二醇的方法，例如从环氧乙烷制备乙二醇，在水、催化剂和可选的二氧化碳的存在下进行。催化剂含有一种两性化合物，例如乙二胺四乙酸(EDTA)。这些双官能化合物具有酸和碱官能团。优选地，本发明中有用的化合物在水中形成缓冲溶液，即酸和碱官能团不完全解离。缓冲溶液的pH值应为2-10，优选为5-10，更优选为4-9。本发明中有用的化合物优选为有机化合物，其中碱官能团和酸官能团之间相隔一个至四个碳原子。
• Detergent additives and detergent compositions containing them
  申请人：UNILEVER PLC

  公开号：EP0070190A1

  公开（公告）日：1983-01-19

  A builder system for detergent compositions comprises 25 to 97% by weight of an aluminosilicate cation-exchange material such as Zeolite A and 3 to 75% by weight, in total, of an organic precipitant builder having a polyvalent anion, for example, an alkyl or alkenyl malonate or succinate, and an organic sequestrant such as a nitrilotriacetate. The ratio of precipitant to sequestrant is 10:1 to 1:10. The builder mix is advantageously used in detergent compositions containing less than 10% inorganic phosphate, and gives good results in zero-phosphate compositions.

  一种用于洗涤剂组合物的增效剂体系包括 25-97%（重量）的硅酸铝阳离子交换材料（如沸石 A）和 3-75%（重量）的具有多价阴离子的有机沉淀剂增效剂（如烷基或烯基丙二酸酯或琥珀酸酯）以及有机螯合剂（如氮基三乙酸酯）。沉淀剂和螯合剂的比例为 10:1 至 1:10。这种增效剂混合物适用于无机磷酸盐含量低于 10%的洗涤剂组合物，在零磷酸盐组合物中也有很好的效果。
• Improved process for the production of alkene oxides
  申请人：UNION CARBIDE CORPORATION

  公开号：EP0127003A1

  公开（公告）日：1984-12-05

  Alkene oxide can be made in a simple, closed process that uses electrolysis to make bromine and hydroxide from bromide and water. The alkene reacts with bromine and then water to form an alkene bromohydrin, which is dehydrobrominated by hydroxide, regenerating bromide, to give alkene oxide. The main by-product in propylene oxide production is 1,2-dibromopropane, made by propylene reacting with bromine and then bromide. Since formation of 1,2-dibromopropane consumes propylene, electrical power, and bromide, which must be recovered, it is desirable to minimize its formation. It has been discovered that adding carbonate and/or bicarbonate to the bromide electrolyte reduces the formation of 1,2-dibromopropane independently of any pH effect. Carbonate/bicarbonate can be used to reduce formation of dibromo-compounds produced in epoxidation of other alkenes using the electrobromohydrin process. Other carboxylic materials, which are functionally similar to bicarbonate, can also reduce formation of dibromo-compounds, as demonstrated using ethylene diamine tetraacetic acid disodium salt to reduce formation of 1,2-dibromopropane in propylene oxide production.

  氧化烯可以通过一种简单的封闭式工艺制造，该工艺使用电解法从溴化物和水制取溴和氢氧化物。烯烃与溴反应，然后与水反应，形成烯烃溴化氢，再与氢氧化物脱氢溴化，再生溴化物，生成环氧烯烃。 环氧丙烷生产过程中的主要副产品是 1,2-二溴丙烷，由丙烯与溴和溴化物反应生成。由于 1,2-二溴丙烷的生成需要消耗丙烯、电能和必须回收的溴化物，因此最好尽量减少其生成。 研究发现，在溴化物电解液中加入碳酸盐和/或碳酸氢盐可减少 1,2-二溴丙烷的形成，而不受 pH 值的影响。 碳酸盐/碳酸氢盐可用于减少使用电溴海因工艺环氧化其他烯烃时产生的二溴化合物的形成。 与碳酸氢盐功能相似的其他羧基材料也可以减少二溴化合物的生成，如使用乙二胺四乙酸二钠盐减少环氧丙烷生产中 1,2-二溴丙烷的生成。
• Treatment of grafted protein latices
  申请人：GENCORP INC.

  公开号：EP0239215A1

  公开（公告）日：1987-09-30

  Ultrasonic irradiation of latices of a graft copolymer of a conjugated diene monomer and a vinyl aryl monomer on a protein such as a soy protein reduces the viscosity and increases the light transmission of the graft copolymer latex. Further improvements in viscosity can be obtained by incrementing the protein into the polymerization reactor during the graft copolymerization process.

  将共轭二烯单体和乙烯基芳基单体的接枝共聚物胶乳超声波辐照在蛋白质（如大豆蛋白）上，可降低接枝共聚物胶乳的粘度并增加其透光率。在接枝共聚过程中，将蛋白质加入聚合反应器中可进一步提高粘度。

表征谱图