[(4R,5S)-2,2-dimethyl-5-(4-methyl-1,3-thiazol-5-yl)-1,3-dioxolan-4-yl]methyl sulfamate

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: [(4R,5S)-2,2-dimethyl-5-(4-methyl-1,3-thiazol-5-yl)-1,3-dioxolan-4-yl]methyl sulfamate
• 化学式: C₁₀H₁₆N₂O₅S₂
• 分子量: 308.4
• InChiKey: STBCVOHBACNUET-SFYZADRCSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.2
• 重原子数：
  19
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.7
• 拓扑面积：
  137
• 氢给体数：
  1
• 氢受体数：
  8

文献信息

• Sulfamate Derivative Compound for Use in Preventing or Treating Epilepsy
  申请人：BIO-PHARM SOLUTIONS, CO., LTD.

  公开号：US20160310461A1

  公开（公告）日：2016-10-27

  The present invention relates to a pharmaceutical composition for treating or preventing epilepsy containing a sulfamate derivative compound and/or pharmaceutically acceptable salt thereof as an active ingredient. Furthermore, the present invention relates to a method for treatment or prevention epilepsy comprising administering a sulfamate derivative compound in a pharmaceutically effective amount to a subject in need of treatment or prevention of epilepsy.
• Sulfamate Derivative Compounds for Use in Treating or Alleviating Pain
  申请人：BIO-PHARM SOLUTIONS ,CO., LTD

  公开号：US20160318894A1

  公开（公告）日：2016-11-03

  The present invention relates to sulfamate derivative compounds and a composition for treating and/or alleviating pain containing the sulfamate derivative compounds or a pharmaceutically acceptable salt thereof as an active ingredient. More specifically, the present invention relates to a pharmaceutical composition for treating or alleviating pain containing a sulfamate derivative compound and/or a pharmaceutically acceptable salt thereof as an active ingredient. Furthermore, the present invention relates to a method for treatment or alleviation of pain comprising administering a sulfamate derivative compound in a pharmaceutically effective amount to a subject in need of treatment or alleviation of pain; and a use of the sulfamate derivative compound or the pharmaceutically acceptable salt thereof in treating and/or alleviating pain, are provided.
• SULFAMATE DERIVATIVE COMPOUNDS FOR USE IN TREATING OR ALLEVIATING A PSYCHIATRIC DISORDER
  申请人：Bio-Pharm Solutions Co., Ltd.

  公开号：US20220218702A1

  公开（公告）日：2022-07-14

  The present invention relates to a pharmaceutical composition for treating and/or alleviating a psychiatric disorder comprising a sulfamate derivative compound and/or a pharmaceutically acceptable salt thereof as an active ingredient. Furthermore, the present invention relates to a pharmaceutical composition for inducing anti-stress, anti-anxiety and/or anti-depressant activities comprising a sulfamate derivative compound and/or a pharmaceutically acceptable salt thereof as an active ingredient.
• US9834535B2
  申请人：——

  公开号：US9834535B2

  公开（公告）日：2017-12-05
• US9937145B2
  申请人：——

  公开号：US9937145B2

  公开（公告）日：2018-04-10