Carbamic acid, (4-(4-bromophenyl)-1H-imidazol-2-YL)-, methyl ester | 41213-94-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: Carbamic acid, (4-(4-bromophenyl)-1H-imidazol-2-YL)-, methyl ester
• 英文别名: methyl N-[5-(4-bromophenyl)-1H-imidazol-2-yl]carbamate
• CAS: 41213-94-9
• 化学式: C₁₁H₁₀BrN₃O₂
• 分子量: 296.12
• InChiKey: IONRYADUAUEBMP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  17
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.09
• 拓扑面积：
  67
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• [EN] NOVEL INHIBITORS OF HEPATITIS C VIRUS REPLICATION<br/>[FR] NOUVEAUX INHIBITEURS DE LA RÉPLICATION DU VIRUS DE L'HÉPATITE C
  申请人：INTERMUNE INC

  公开号：WO2012087976A2

  公开（公告）日：2012-06-28

  The embodiments provide compounds of the general Formulae XV, XVI, XVII and XVIII as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods of treating a hepatitis C virus infection and methods of treating liver fibrosis, the methods generally involving administering to an individual in need thereof an effective amount of a subject compound or composition.