(E)-1-[4-(difluoromethylsulfonyl)phenyl]-3-[4-(dimethylamino)phenyl]prop-2-en-1-one

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 直链 1,3-二芳基丙烷
• 英文名称: (E)-1-[4-(difluoromethylsulfonyl)phenyl]-3-[4-(dimethylamino)phenyl]prop-2-en-1-one
• 化学式: C₁₈H₁₇F₂NO₃S
• 分子量: 365.4
• InChiKey: XQTGEXIZNLWJTP-LFYBBSHMSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  25
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  62.8
• 氢给体数：
  0
• 氢受体数：
  6

文献信息

• Lipoprotein assay
  申请人：——

  公开号：US20030101004A1

  公开（公告）日：2003-05-29

  A method of assaying to determine the identity and/or concentration or relative concentration in a sample solution of a particular one of a number of different target molecule types, comprise the steps of: i) adding to the sample a probe substance which binds to the or each target molecule type and which when so bound fluoresces under appropriate excitation; ii) performing a time-resolved fluorescence measurement on the sample; and iii) making said determination from analysis of the time decay data obtained from said time-resolved fluorescence measurement.

  一种确定样品溶液中多种不同目标分子类型中特定一种的特性和/或浓度或相对浓度的化验方法，包括以下步骤：i) 向样品中加入一种探针物质，该探针物质与上述或每种目标分子类型结合，结合后在适当的激发下发出荧光；ii) 对样品进行时间分辨荧光测量；iii) 通过分析从上述时间分辨荧光测量中获得的时间衰减数据进行上述确定。
• LIPOPROTEIN ASSAY
  申请人：Council for the Central Laboratory of the Research Councils

  公开号：EP1259805A1

  公开（公告）日：2002-11-27
• VERFAHREN ZUR HERSTELLUNG VON AlKYLVERBRÜCKTEN LIGANDSYSTEMEN UND ÜBERGANGSMETALLVERBINDUNGEN
  申请人：Basell Polyolefine GmbH

  公开号：EP1313747B1

  公开（公告）日：2005-04-20
• ASSAY FOR GENERATION OF A LIPID PROFILE USING FLUORESCENCE MEASUREMENT
  申请人：Science and Technology Facilities Council

  公开号：EP1828781A1

  公开（公告）日：2007-09-05
• Assay For Lipoproteins Using Lumiphore K-37
  申请人：Jones Gareth Royston

  公开号：US20080118990A1

  公开（公告）日：2008-05-22

  The present invention relates to a method of determining the concentration of total lipoprotein in sample solution. The method comprising the steps of adding to an aliquot of the sample a probe substance, K- 37 which binds to lipoproteins in the sample, and which when so bound fluoresces under appropriate excitation. The total lipoprotein concentration in the sample is then determined using fluorescence analysis. The method may employ a second probe substance that is specific to a class or sub-class of lipoproteins in order that the user may distinguish between lipoproteins. The invention further relates to apparatus which may be used to perform the methods of the invention.