1,5-Dimethyl-2-phenyl-4-(propan-2-ylamino)pyrazol-3-one;hydron;chloride | 13576-96-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 1,5-Dimethyl-2-phenyl-4-(propan-2-ylamino)pyrazol-3-one;hydron;chloride
• 英文别名: 1,5-dimethyl-2-phenyl-4-(propan-2-ylamino)pyrazol-3-one;hydron;chloride
• CAS: 13576-96-0
• 化学式: C14H20ClN3O
• mdl: MFCD00800727
• 分子量: 281.78
• InChiKey: WJPVTNJDDFIBKU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.54
• 重原子数：
  19
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.357
• 拓扑面积：
  35.6
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• METHODS AND COMPOSITIONS FOR TREATING INFECTION
  申请人：UNIVERSITY OF ROCHESTER

  公开号：US20150238473A1

  公开（公告）日：2015-08-27

  Provided herein are compositions and methods for treating or preventing infection.

  本文提供了用于治疗或预防感染的组合物和方法。
• Methods and compositions for treating infection
  申请人：UNIVERSITY OF ROCHESTER

  公开号：US10004701B2

  公开（公告）日：2018-06-26

  Provided herein are compositions and methods for treating or preventing infection.

  本文提供了用于治疗或预防感染的组合物和方法。
• Chemical Proteomic Assay for Optimizing Drug Binding to Target Proteins
  申请人：Sem Daniel S.

  公开号：US20100304998A1

  公开（公告）日：2010-12-02

  Disclosed herein are methods related to drug development. The methods typically include steps whereby an existing drug is modified to obtain a derivative form or whereby an analog of an existing drug is identified in order to obtain a new therapeutic agent that preferably has a higher efficacy and fewer side effects than the existing drug.
• Chemical Fragment Screening and Assembly Utilizing Common Chemistry for NMR Probe Introduction and Fragment Linkage
  申请人：Sem Daniel S.

  公开号：US20100305326A1

  公开（公告）日：2010-12-02

  Disclosed herein are methods related to drug development. The methods typically include steps whereby two chemical fragments are identified as binding to a target protein and subsequently the two chemical fragments are joined to create a new chemical entity that binds to the target protein.
• METHODS AND COMPOUNDS FOR REDUCING INTRACELLULAR LIPID STORAGE
  申请人：Wu Sean

  公开号：US20130023488A1

  公开（公告）日：2013-01-24

  Compounds and compositions for reducing intracellular lipid accumulation in a cell are described herein. These compounds are useful for the treatment and prevention of lipid/glycogen disorders, as well as for the treatment and prevention of obesity. A high throughput screen for identifying compounds that reduce intracellular lipid accumulation in cells is also provided.