5-(Trifluoromethyl)-1-phenyl-N-ethyl-1H-pyrazole-4-carboxamide | 98534-36-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 5-(Trifluoromethyl)-1-phenyl-N-ethyl-1H-pyrazole-4-carboxamide
• 英文别名: 1H-Pyrazole-4-carboxamide, N-ethyl-1-phenyl-5-(trifluoromethyl)-；N-ethyl-1-phenyl-5-(trifluoromethyl)pyrazole-4-carboxamide
• CAS: 98534-36-2
• 化学式: C₁₃H₁₂F₃N₃O
• 分子量: 283.253
• InChiKey: BHCMEXZOEDQEJJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  20
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.23
• 拓扑面积：
  46.9
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• Processes and intermediates for preparing fused heterocyclic kinase inhibitors
  申请人：Raeppel Franck

  公开号：US20090286984A1

  公开（公告）日：2009-11-19

  This invention relates to processes and intermediates for manufacturing fused heterocyclic-type kinase inhibitor compounds, such as thienopyridine-based compounds, and to processes and intermediates for preparing intermediates that are useful in the manufacture of fused heterocyclic-type kinase inhibitor compounds, such as thienopyridine-based compounds, particularly at an industrial level.

  本发明涉及用于制造融合杂环型激酶抑制剂化合物的过程和中间体，例如噻吩并吡啶基化合物，并涉及用于制备在制造融合杂环型激酶抑制剂化合物，例如噻吩并吡啶基化合物中有用的中间体的过程和中间体，特别是在工业水平上。
• PROCESSES AND INTERMEDIATES FOR PREPARING FUSED HETEROCYCLIC KINASE INHIBITORS
  申请人：Raeppel Franck

  公开号：US20120095234A1

  公开（公告）日：2012-04-19

  This invention relates to processes and intermediates for manufacturing fused heterocyclic-type kinase inhibitor compounds, such as thienopyridine-based compounds, and to processes and intermediates for preparing intermediates that are useful in the manufacture of fused heterocyclic-type kinase inhibitor compounds, such as thienopyridine-based compounds, particularly at an industrial level.

  本发明涉及制造融合杂环型激酶抑制剂化合物（例如基于噻吩并吡啶的化合物）的过程和中间体，以及制备有用于制造融合杂环型激酶抑制剂化合物（例如基于噻吩并吡啶的化合物）的中间体的过程和中间体，特别是在工业水平上。
• Herbicidal pyrazole-(thio)-carboxamides
  申请人：ELI LILLY AND COMPANY

  公开号：EP0151866A2

  公开（公告）日：1985-08-21

  57 1,5-Disubstituted-1H-pyrazole-4-carboxamide derivatives, useful as herbicides and aquatic algicides.

  57 1,5-二取代-1H-吡唑-4-甲酰胺衍生物，可用作除草剂和水生杀藻剂。
• US4620865A
  申请人：——

  公开号：US4620865A

  公开（公告）日：1986-11-04
• US8907091B2
  申请人：——

  公开号：US8907091B2

  公开（公告）日：2014-12-09