Ethyl 12-[7-(11-ethoxy-11-oxoundecyl)-2,3,10-trimethyl-6,11-dioxo-1,4-dioxa-10-aza-7-azoniacyclododec-7-yl]dodecanoate | 58801-34-6

• 物质功能分类: 分析化学 - 分析试剂 - 常用分析试剂
• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: Ethyl 12-[7-(11-ethoxy-11-oxoundecyl)-2,3,10-trimethyl-6,11-dioxo-1,4-dioxa-10-aza-7-azoniacyclododec-7-yl]dodecanoate
• CAS: 58801-34-6
• 化学式: C38H71N2O8+
• 分子量: 684.0
• InChiKey: ZMCUZULVZVMNMY-UHFFFAOYSA-N

物化性质

• 沸点：
  715.1±50.0 °C(Predicted)
• 密度：
  1.000±0.06 g/cm3(Predicted)
• 溶解度：
  溶于二甲基亚砜

计算性质

• 辛醇/水分配系数(LogP)：
  8.4
• 重原子数：
  48
• 可旋转键数：
  27
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  108
• 氢给体数：
  0
• 氢受体数：
  8

安全信息

• WGK Germany：
  3

制备方法与用途

生物活性方面，钙离子载体I (ETH 1001) 是一种用于生物膜的选择性Ca²⁺ 载体。它可应用于Ca²⁺ 选择性微电极，适用于定量测定细胞内静息Ca²⁺ 活性和缓慢变化的Ca²⁺水平。

文献信息

• CELL ANALYSIS USING CHEMFET SENSOR ARRAY-BASED SYSTEMS
  申请人：Life Technologies Corporation

  公开号：EP3850350A1

  公开（公告）日：2021-07-21
• [EN] CELL ANALYSIS USING CHEMFET SENSOR ARRAY-BASED SYSTEMS<br/>[FR] ANALYSE DE CELLULES UTILISANT DES SYSTÈMES BASÉS SUR UN RÉSEAU DE CAPTEURS CHEMFET
  申请人：LIFE TECHNOLOGIES CORP

  公开号：WO2020056039A1

  公开（公告）日：2020-03-19

  Various cell analysis systems of the present teachings can measure the electrical and metabolic activity of single, living cells with subcellular addressability and simultaneous data acquisition for between about 10 cells to about 500,000 cells in a single analysis. Various sensor array devices of the present teachings can have sensor arrays with between 20 million to 660 million ChemFET sensors built into a massively paralleled array and can provide for simultaneous measurement of cells with data acquisition rates in the kilohertz (kHz) range. As various ChemFET sensor arrays of the present teachings can detect chemical analytes as well detect changes in cell membrane potential, various cell analysis systems of the present teachings also provide for the controlled chemical and electrical interrogation of cells. The frame rate can be increased by selecting a smaller subset of pixels to monitor, i.e. by windowing down the area of a sensor array device over which data is collected.