1-(2-chloroethyl)-2-methylimidazole;hydron;chloride

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 1-(2-chloroethyl)-2-methylimidazole;hydron;chloride
• 化学式: C6H10Cl2N2
• 分子量: 181.06
• InChiKey: ANZFVGZRGNLSBV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.85
• 重原子数：
  10
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  17.8
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• PHARMACEUTICAL 6,5 HETEROBICYCLIC RING DERIVATIVES
  申请人：UCB Biopharma SPRL

  公开号：EP3527209A1

  公开（公告）日：2019-08-21

  The invention relates to 6,5 heterobicyclic ring derivatives, processes for preparing them, pharmaceutical compositions containing them and their use for the treatment of inflammatory conditions driven by STING activation, such as SLE and geographic atrophy.

  该发明涉及6,5杂环环衍生物，其制备方法，含有它们的药物组合物以及它们用于治疗由STING激活驱动的炎症性疾病，如SLE和地理性萎缩症。
• Fluorinated ionic liquids with high oxygen solubility for metal-air batteries
  申请人：TOYOTA MOTOR EUROPE

  公开号：US11121422B2

  公开（公告）日：2021-09-14

  Ionic compounds containing an anion, and a cation having the following structural formula (1): R1R2R3N+-(linker1)-O-(linker2)-(FC)  (1) wherein: R1 and R2 either linear or branched alkyl groups or together form a N-heterocylic ring with the nitrogen atom to which they are joined; R3 is linear or branched alkyl group; linker1 and linker2 are alkylene chains or polyether chains; and the group FC is a fluorinated alkyl group, as well as an electrolyte material comprising such an ionic compound and a metal salt, and metal-air batteries using such an electrolyte material. The invention also relates to a metal-air battery containing an electrolyte material, wherein the electrolyte material comprises at least one ionic compound and a metal salt, and wherein at least one ionic compound contains an anion CnF2n+1COO− or CnF2n+1SO3−, where in each case n is at least 1 and at most 10.

  含有一个阴离子和一个阳离子的离子化合物，其结构式如下(1)： R1R2R3N+-(linker1)-O-(linker2)-(FC) (1) 其中R1和R2为直链或支链烷基，或与氮原子共同形成N-杂环；R3为直链或支链烷基；连接体1和连接体2为亚烷基链或聚醚链；基团FC为氟化烷基，以及由这种离子化合物和金属盐组成的电解质材料和使用这种电解质材料的金属空气电池。本发明还涉及一种含有电解质材料的金属空气电池，其中电解质材料包含至少一种离子化合物和金属盐，且至少一种离子化合物包含阴离子 CnF2n+1COO- 或 CnF2n+1SO3-，在每种情况下 n 至少为 1，最多为 10。
• FLUORINATED IONIC LIQUIDS WITH HIGH OXYGEN SOLUBILITY FOR METAL-AIR BATTERIES
  申请人：TOYOTA MOTOR EUROPE

  公开号：US20190190104A1

  公开（公告）日：2019-06-20

  Ionic compounds containing an anion, and a cation having the following structural formula (1): R 1 R 2 R 3 N + -(linker 1 )-O-(linker 2 )-(FC)  (1) wherein: R 1 and R 2 either linear or branched alkyl groups or together form a N-heterocylic ring with the nitrogen atom to which they are joined; R 3 is linear or branched alkyl group; linker 1 and linker 2 are alkylene chains or polyether chains; and the group FC is a fluorinated alkyl group, as well as an electrolyte material comprising such an ionic compound and a metal salt, and metal-air batteries using such an electrolyte material. The invention also relates to a metal-air battery containing an electrolyte material, wherein the electrolyte material comprises at least one ionic compound and a metal salt, and wherein at least one ionic compound contains an anion C n F 2n+1 COO − or C n F 2n+1 SO 3 − , where in each case n is at least 1 and at most 10.
• Pharmaceutical 6,5 Heterobicyclic Ring Derivatives
  申请人：UCB Biopharma SRL

  公开号：US20200399268A1

  公开（公告）日：2020-12-24

  The invention relates to 6,5 heterobicyclic ring derivatives of formula (I), processes for preparing them, pharmaceutical compositions containing them and their use for the treatment of inflammatory conditions driven by STING activation, such as, but not confined to, SLE and geographic atrophy.