Carboxymethyl-tributyl-phosphonium

• 分子结构分类: 有机化合物 - 有机磷化合物 - 四烷基鏻化合物
• 英文名称: Carboxymethyl-tributyl-phosphonium
• 英文别名: tributylphosphonium acetic acid；Tributyl(carboxymethyl)phosphanium
• 化学式: C₁₄H₃₀O₂P
• 分子量: 261.365
• InChiKey: IJKVLGNJMBTRIP-UHFFFAOYSA-O

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  17
• 可旋转键数：
  11
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.93
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  Carboxymethyl-tributyl-phosphonium 、 2-(2-(4-mercaptophenyl)acetamide)ethane-1-sulfonic acid 在 benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate 、 N,N-二异丙基乙胺 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 生成 (2-(2-(4-((tributylphosphonio)acetyl)thio)phenyl)acetamido)ethane-1-sulfonate
  参考文献：
  名称：

  Phosphonium Compound, Reagent Kit for Derivatization, Mass Spectrometric Method, and Method for Producing Phosphonium Compound

  摘要：

  Provided is a phosphonium compound represented by Formula (I): in Formula (I), R 1 , R 2 , and R 3 are independently from each other, an alkyl group or an aryl group, the alkyl group is a substituted or unsubstituted, linear or branched alkyl group having 1 to 20 carbon atoms or a substituted or unsubstituted cyclic alkyl group having 5 to 20 carbon atoms, the aryl group is a substituted or unsubstituted aryl group having 6 to 20 carbon atoms; X is a reactive group having a hydrazide group, a halide group, a pseudohalide group, or a thioester group; and Y − is an anion having a total charge of −1, or Y − is absence.

  公开号：

  US20230112623A1
• 作为产物：
  描述：

  三丁基膦 、 溴乙酸叔丁酯 在 三氟乙酸 作用下， 以 甲苯 为溶剂， 以0.89 g的产率得到Carboxymethyl-tributyl-phosphonium
  参考文献：
  名称：

  Phosphonium Compound, Reagent Kit for Derivatization, Mass Spectrometric Method, and Method for Producing Phosphonium Compound

  摘要：

  Provided is a phosphonium compound represented by Formula (I): in Formula (I), R 1 , R 2 , and R 3 are independently from each other, an alkyl group or an aryl group, the alkyl group is a substituted or unsubstituted, linear or branched alkyl group having 1 to 20 carbon atoms or a substituted or unsubstituted cyclic alkyl group having 5 to 20 carbon atoms, the aryl group is a substituted or unsubstituted aryl group having 6 to 20 carbon atoms; X is a reactive group having a hydrazide group, a halide group, a pseudohalide group, or a thioester group; and Y − is an anion having a total charge of −1, or Y − is absence.

  公开号：

  US20230112623A1

文献信息

• Phosphonium Compound, Reagent Kit for Derivatization, Mass Spectrometric Method, and Method for Producing Phosphonium Compound
  申请人：JEOL Ltd.

  公开号：US20230112623A1

  公开（公告）日：2023-04-13

  Provided is a phosphonium compound represented by Formula (I): in Formula (I), R 1 , R 2 , and R 3 are independently from each other, an alkyl group or an aryl group, the alkyl group is a substituted or unsubstituted, linear or branched alkyl group having 1 to 20 carbon atoms or a substituted or unsubstituted cyclic alkyl group having 5 to 20 carbon atoms, the aryl group is a substituted or unsubstituted aryl group having 6 to 20 carbon atoms; X is a reactive group having a hydrazide group, a halide group, a pseudohalide group, or a thioester group; and Y − is an anion having a total charge of −1, or Y − is absence.