N-[(Z)-[(E)-3-(5-nitrofuran-2-yl)prop-2-enylidene]amino]-2-(prop-2-enylamino)-1,3-thiazole-4-carboxamide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: N-[(Z)-[(E)-3-(5-nitrofuran-2-yl)prop-2-enylidene]amino]-2-(prop-2-enylamino)-1,3-thiazole-4-carboxamide
• 化学式: C14H13N5O4S
• 分子量: 347.35
• InChiKey: RRYRUSPVJFWMBE-BJUKAYDCSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  24
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  154
• 氢给体数：
  2
• 氢受体数：
  8

文献信息

• Wound closure systems for reducing surgical site infections comprising incision drapes filled with releasable antimicrobial agents
  申请人：Ethicon, Inc.

  公开号：US11452641B2

  公开（公告）日：2022-09-27

  A surgical incision drape, comprises a flexible substantially flat areal substrate having an upper side and an opposing tissue-facing side, having a longitudinal axis and a pressure sensitive adhesive disposed on the tissue-facing side; at least one hollow microtubular compartment containing a flowable medical agent, said hollow microtubular compartment positioned to intersect the longitudinal axis and embedded into the substrate or positioned on the substrate.

  一种手术切口敷料，包括一个柔性大体平坦的基底，基底有一个上侧和一个相对的面向组织的侧，基底有一个纵轴，面向组织的侧上有一个压敏粘合剂；至少一个中空微管隔室，内装可流动的医用制剂，所述中空微管隔室的位置与纵轴相交，并嵌入基底或设置在基底上。
• WOUND CLOSURE SYSTEMS FOR REDUCING SURGICAL SITE INFECTIONS COMPRISING INCISION DRAPES FILLED WITH RELEASABLE ANTIMICROBIAL AGENTS
  申请人：Ethicon, Inc

  公开号：EP3989865A1

  公开（公告）日：2022-05-04
• Wound Closure Systems for Reducing Surgical Site Infections Comprising Incision Drapes Filled with Releasable Antimicrobial Agents
  申请人：Ethicon, Inc.

  公开号：US20200405544A1

  公开（公告）日：2020-12-31

  A surgical incision drape, comprises a flexible substantially flat areal substrate having an upper side and an opposing tissue-facing side, having a longitudinal axis and a pressure sensitive adhesive disposed on the tissue-facing side; at least one hollow microtubular compartment containing a flowable medical agent, said hollow microtubular compartment positioned to intersect the longitudinal axis and embedded into the substrate or positioned on the substrate.
• [EN] WOUND CLOSURE SYSTEMS FOR REDUCING SURGICAL SITE INFECTIONS COMPRISING INCISION DRAPES FILLED WITH RELEASABLE ANTIMICROBIAL AGENTS<br/>[FR] SYSTÈMES DE FERMETURE DE PLAIE POUR RÉDUIRE DES INFECTIONS DE SITE CHIRURGICAL COMPRENANT DES CHAMPS OPÉRATOIRES D'INCISION REMPLIS AVEC DES AGENTS ANTIMICROBIENS LIBÉRABLES
  申请人：ETHICON INC

  公开号：WO2020261025A1

  公开（公告）日：2020-12-30

  A surgical incision drape (10), comprises a flexible substantially flat areal substrate (20) having an upper side (22) and an opposing tissue-facing side, having a longitudinal axis (21) and a pressure sensitive adhesive (40) disposed on the tissue-facing side; at least one hollow microtubular compartment (30) containing a flowable medical agent (100), said hollow microtubular compartment (30) positioned to intersect the longitudinal axis (21) and embedded into the substrate (20) or positioned on the substrate (20).