[2-甲基-1-[(1-甲基-2-哌啶基)甲基]-6-硝基-1H-吲哚-3-基]-1-萘基甲酮 | 335160-53-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 中文名称: [2-甲基-1-[(1-甲基-2-哌啶基)甲基]-6-硝基-1H-吲哚-3-基]-1-萘基甲酮
• 英文名称: 1-((N-Methylpiperidin-2-yl)methyl)-2-methyl-3-(naphthalen-1-oyl)-6-nitroindole
• 英文别名: [2-methyl-1-[(1-methylpiperidin-2-yl)methyl]-6-nitroindol-3-yl]-naphthalen-1-ylmethanone
• CAS: 335160-53-7
• 化学式: C27H27N3O3
• 分子量: 441.5
• InChiKey: QGNIEJBBHMMNOZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.7
• 重原子数：
  33
• 可旋转键数：
  4
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  71.1
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• Methods and compositions for treating mucusal tissue disorders
  申请人：The University of North Carolina at Chapel Hill

  公开号：US10406200B2

  公开（公告）日：2019-09-10

  The present invention provides compositions and formulations comprising glutathione with or without thiocyanate and methods of use thereof to treat diseases and disorders in mucosal/epithelial tissue.

  本发明提供了包含谷胱甘肽（含或不含硫氰酸盐）的组合物和制剂及其用于治疗粘膜/上皮组织疾病和失调的方法。
• Methods and compositions for treating mucosal tissue disorders
  申请人：The University of North Carolina at Chapel Hill

  公开号：US11058743B2

  公开（公告）日：2021-07-13

  The present invention provides compositions and formulations comprising glutathione with or without thiocyanate and methods of use thereof to treat diseases and disorders in mucosal/epithelial tissue.

  本发明提供了包含谷胱甘肽（含或不含硫氰酸盐）的组合物和制剂及其用于治疗粘膜/上皮组织疾病和失调的方法。
• Methods and Compositions for Treating Mucosal Tissue Disorders
  申请人：The University of North Carolina at Chapel Hill

  公开号：US20150010654A1

  公开（公告）日：2015-01-08

  The present invention provides compositions and formulations comprising glutathione with or without thiocyanate and methods of use thereof to treat diseases and disorders in mucosal/epithelial tissue.
• METHODS AND COMPOSITIONS FOR TREATING MUCUSAL TISSUE DISORDERS
  申请人：The University of North Carolina at Chapel Hill

  公开号：US20160228490A1

  公开（公告）日：2016-08-11

  The present invention provides compositions and formulations comprising glutathione with or without thiocyanate and methods of use thereof to treat diseases and disorders in mucosal/epithelial tissue.
• METHODS AND COMPOSITIONS FOR TREATING MUCOSAL TISSUE DISORDERS
  申请人：The University of North Carolina at Chapel Hill

  公开号：US20200179478A1

  公开（公告）日：2020-06-11

  The present invention provides compositions and formulations comprising glutathione with or without thiocyanate and methods of use thereof to treat diseases and disorders in mucosal/epithelial tissue.