4-(5-Methyl-1,2,4-oxadiazol-3-YL)benzonitrile | 200880-45-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 4-(5-Methyl-1,2,4-oxadiazol-3-YL)benzonitrile
• CAS: 200880-45-1
• 化学式: C₁₀H₇N₃O
• mdl: MFCD09746374
• 分子量: 185.18
• InChiKey: DILHKCVXZZTARQ-UHFFFAOYSA-N

物化性质

• 沸点：
  361.0±44.0 °C(Predicted)
• 密度：
  1.28±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  14
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  62.7
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• LSD1 INHIBITOR AND PREPARATION METHOD AND APPLICATION THEREOF
  申请人：MEDSHINE DISCOVERY INC.

  公开号：US20200345700A1

  公开（公告）日：2020-11-05

  A cyclopropylamine compound as a lysine-specific demethylase 1 (LSD1) inhibitor. Particularly, the present invention relates to a compound represented by formula (I) and a pharmaceutically acceptable salt thereof. The present invention also provides an application of the same in preparing a drug for treating an LSD1-related disease.