1-(2,4-dichlorophenyl)-5-(5-(3-(dimethylamino)prop-1-ynyl)thiophen-2-yl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide | 1020106-43-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 1-(2,4-dichlorophenyl)-5-(5-(3-(dimethylamino)prop-1-ynyl)thiophen-2-yl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide
• 英文别名: 1-(2,4-Dichloro-phenyl)-5-[5-(3-dimethylamino-prop-1-ynyl)-thiophen-2-yl]-4-methyl-1H-pyrazole-3-carboxylic acid piperidin-1-ylamide；1-(2,4-Dichlorophenyl)-5-(5-(3-(dimethylamino)prop-1-ynyl)-thiophen-2-yl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide；1-(2,4-dichlorophenyl)-5-[5-[3-(dimethylamino)prop-1-ynyl]thiophen-2-yl]-4-methyl-N-piperidin-1-ylpyrazole-3-carboxamide
• CAS: 1020106-43-7
• 化学式: C₂₅H₂₇Cl₂N₅OS
• 分子量: 516.494
• InChiKey: PMRSQJWWRFFSLF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.8
• 重原子数：
  34
• 可旋转键数：
  6
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  81.6
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• THIOPHENE COMPOUNDS
  申请人：Shia Kak-Shan

  公开号：US20080090810A1

  公开（公告）日：2008-04-17

  This invention relates to thiophene compounds of formula (I) shown below: Each variable in formula (I) is defined in the specification. These compounds can be used to treat cannabinoid-receptor mediated disorders.

  本发明涉及如下所示的公式（I）的噻吩化合物：公式（I）中的每个变量在规范中有定义。这些化合物可用于治疗大麻素受体介导的疾病。
• Thiophene Compounds
  申请人：Shia Kak-shan

  公开号：US20090029969A2

  公开（公告）日：2009-01-29

  This invention relates to thiophene compounds of formula (I) shown below: Each variable in formula (I) is defined in the specification. These compounds can be used to treat cannabinoid-receptor mediated disorders.
• US7834046B2
  申请人：——

  公开号：US7834046B2

  公开（公告）日：2010-11-16