5-Methyl-1-(2-methylphenyl)-1H-tetrazole | 62306-09-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 5-Methyl-1-(2-methylphenyl)-1H-tetrazole
• 英文别名: 5-methyl-1-(2-methylphenyl)tetrazole
• CAS: 62306-09-6
• 化学式: C₉H₁₀N₄
• 分子量: 174.2
• InChiKey: FMCBMFSNVKWSHP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  13
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  43.6
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• NOVEL ANTIBIOTICS
  申请人：Schuren Frank Henri Johan

  公开号：US20100130509A1

  公开（公告）日：2010-05-27

  The invention relates to the field of antibiotic compositions, both inside and outside the medical field. Presented is a new class of antibiotic compounds, variants of bis(1-aryl-5-tetrazolyl)methanes, which are especially useful for combating infections with gram-positive bacteria and especially MRSA.

  本发明涉及抗生素组合物的领域，包括医学领域内外。介绍了一种新的抗生素化合物类别，即双(1-芳基-5-四唑基)甲烷的变体，它们特别适用于对抗革兰氏阳性菌感染，尤其是耐甲氧西林金黄色葡萄球菌感染。
• Alkoxy-(tetrazol-1-yl)benzaldehyde compound and process for producing the same
  申请人：Hagiya Kazutake

  公开号：US20070060630A1

  公开（公告）日：2007-03-15

  The present invention relates to a process for producing an alkoxy-(tetrazol-1-yl)benzaldehyde compound represented by Formula (2): wherein A 1 is an alkoxy group, and A 2 is a hydrogen atom, alkyl group or fluorine-substituted alkyl group, the process comprising reacting a 1-(alkoxyphenyl)-1H-tetrazole compound represented by Formula (1): wherein A 1 and A 2 are as defined above, with hexamethylenetetramine in a sulfonic acid solvent, followed by hydrolysis. According to the present invention, an alkoxy-(tetrazol-1-yl)benzaldehyde compound can be safely and efficiently produced by formylating a 1-(alkoxyphenyl)-1H-tetrazole compound.
• US7579480B2
  申请人：——

  公开号：US7579480B2

  公开（公告）日：2009-08-25