nona-4t,7t-dienoic acid | 64807-33-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: nona-4t,7t-dienoic acid
• 英文别名: 7-Nonadienoic acid；(4E,7E)-nona-4,7-dienoic acid
• CAS: 64807-33-6
• 化学式: C₉H₁₄O₂
• 分子量: 154.209
• InChiKey: OFCFHLUHCYFRBN-ZIMISOLQSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  11
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  nona-4t,7t-dienoic acid 在 lithium aluminium tetrahydride 作用下， 以 乙醚 为溶剂， 以98%的产率得到(4E,7E)-4,7-nonadienyl-1-ol
  参考文献：
  名称：

  Total syntheses of (.+-.)-cerulenin, (.+-.)-tetrahydrocerulenin and related compounds

  摘要：

  DOI：

  10.1021/jo00346a016
• 作为产物：
  描述：

  Trimethyl-[1-((E)-1-vinyl-pent-3-enyloxy)-vinyloxy]-silane 以 四氢呋喃 为溶剂， 生成 nona-4t,7t-dienoic acid
  参考文献：
  名称：

  SEQUENTIAL [2,3]WITTIG AND CLAISEN REARRANGEMENT: A FACILE SYNTHETIC METHOD FOR (E,E)-4,7-ALKADIENALS AND -ALKADIENOIC ACIDS. A NEW FORMAL SYNTHESIS OF (±)-CERULENIN

  摘要：

  双烯丙基醚的亲区选择性[2,3]Wittig重排，以及随后的Claisen重排，可以方便地得到（E,E）-4,7-烯丙二烯醛和烯丙二烯酸。在具有多种生物活性的（±）-青霉烯素的新形式合成中，展示了西格马拓扑序列的多功能性。

  DOI：

  10.1246/cl.1981.1721

文献信息

• Process for the carbonylation of butadiene and/or butadiene derivative
  申请人：DSM N.V.

  公开号：EP1085004A1

  公开（公告）日：2001-03-21

  Process for the carbonylation of butadiene and/or at least one butadiene derivative in the presence of carbon monoxide, an alcohol and/or water, a rhodium-containing catalyst and an iodide containing promotor, wherein the carbonylation and/or carbonylation product recovery is performed in the presence of at least one stabilizer compound selected from a compound of an element of any of the groups 1-2 of the Periodic Table, a first row transition metal compound of any of the groups 3-12 of the Periodic Table, a compound of an element of group 13 of the Periodic Table, a compound of an element of group 15 of the Periodic Table, a rhenium compound, an iridium compound, a platinum compound and a cerium compound.

  在存在一氧化碳、醇和/或水、含铑催化剂和含碘促进剂的情况下，对丁二烯和/或至少一种丁二烯衍生物进行羰基化的过程，其中羰基化和/或羰基化产品的回收是在至少选择自周期表1-2组元素的化合物、周期表3-12组过渡金属化合物的第一行、周期表13组元素化合物、周期表15组元素化合物、铼化合物、铱化合物、铂化合物和铈化合物中选择的至少一种稳定剂化合物的存在下进行的。
• Process for the carbonylation of butadiene and/or at least one butadiene derivative
  申请人：DSM N.V.

  公开号：EP1118607A1

  公开（公告）日：2001-07-25

  Process for the carbonylation of butadiene and/or at least one butadiene derivative in the presence of water, an alkyl iodide and a rhodium containing catalyst system, wherein the carbonylation is performed in the presence of a carboxylic acid and the amount of water is higher than 0.4 wt.% and less than or equal to 5 wt.% (relative to the total liquid reaction mixture including the solvent(s), catalyst(s), promotor(s) and reactants).

  在水、烷基碘化物和含铑催化剂体系存在下对丁二烯和/或至少一种丁二烯衍生物进行羰基化的工艺，其中羰基化是在羧酸存在下进行的，水的用量大于 0.4 重量％且小于或等于 5 重量％（相对于包括溶剂、催化剂、促进剂和反应物在内的总液体反应混合物而言）。
• A total synthesis of -cerulenin and -tetrahydrocerulenin
  作者：Ann A. Jakubowski、Frank S. Guziec、Max Tishler

  DOI：10.1016/s0040-4039(01)83776-x

  日期：1977.1
• [EN] PROCESS FOR THE PREPARATION OF 3-PENTENOIC ACID AND/OR ESTER THEREOF STARTING FROM BUTADIENE<br/>[FR] PROCEDE DE PREPARATION D'ACIDE 3-PENTANOIQUE A PARTIR DE BUTADIENE ET/OU ESTER DE CE DERNIER
  申请人：DSM NV

  公开号：WO2001021569A1

  公开（公告）日：2001-03-29

  Process for the preparation of 3-pentenoic acid and/or ester thereof starting from butadiene, wherein the process comprises the following steps : (a) reacting butadiene with a hydroxy group containing compound into an allylic compound, (b) separating the allylic compound from the reaction mixture obtained in step (a), (c) carbonylating the allylic compound in the presence of carbon monoxide and an alcohol and/or water using a rhodium containing catalyst and an iodine promotor whereby the carbonylation and/or carbonylation product recovery is performed in the presence of at least one stabilizer compound selected from a compound of an element of any of the groups 1-2 of the Periodic Table, a first row transition metal compound of any of the groups 3-12 of the Periodic Table, a compound of an element of group 13 of the Periodic Table, a compound of an element of group 15 of the Periodic Table, a rhenium compound, an iridium compound, a platinum compound and a cerium compound.
• [EN] PROCESS FOR THE CARBONYLATION OF BUTADIENE AND/OR AT LEAST ONE BUTADIENE DERIVATIVE<br/>[FR] PROCEDE DE CARBONYLATION DE BUTADIENE ET/OU D'AU MOINS UN DERIVE DE BUTADIENE
  申请人：DSM NV

  公开号：WO2001053249A1

  公开（公告）日：2001-07-26

  Process for the carbonylation of butadiene and/or at least one butadiene derivative in the presence of water, an alkyl iodide and a rhodium containing catalyst system, wherein the carbonylation is performed in the presence of a carboxylic acid and the amount of water is higher than 0.4 wt. % and less than or equal to 5 wt. % (relative to the total liquid reaction mixture including the solvent(s), catalyst(s), promotor(s) and reactants).