5-[Difluoro-(4-pentyl-cyclohexyl)-methoxy]-1,2,3-trifluoro-benzene | 208338-57-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 5-[Difluoro-(4-pentyl-cyclohexyl)-methoxy]-1,2,3-trifluoro-benzene
• 英文别名: 5-[Difluoro(4-pentylcyclohexyl)methoxy]-1,2,3-trifluorobenzene；5-[difluoro-(4-pentylcyclohexyl)methoxy]-1,2,3-trifluorobenzene
• CAS: 208338-57-2
• 化学式: C₁₈H₂₃F₅O
• 分子量: 350.372
• InChiKey: ALWBMRSWQMGAMX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.8
• 重原子数：
  24
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  对戊基环己酮 在 palladium on activated charcoal 氢气 、 溴 、 potassium carbonate 、 六乙基亚磷酸胺 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 生成 5-[Difluoro-(4-pentyl-cyclohexyl)-methoxy]-1,2,3-trifluoro-benzene
  参考文献：
  名称：

  Synthesis and Properties of Novel Liquid Crystalline Compounds having a Difluoromethyleneoxy Moiety as a Linkage Group

  摘要：

  Novel liquid crystal compounds having a difluoromethyleneoxy group as a linkage group have been prepared by the new synthetic method using dibromo-difluoromethane in good yield. From. the results of physical property measurements; i.e., transition temperature, dielectric anisotropy (Deltaepsilon), birefringence (Deltan) and viscosity, it becomes obvious that the derivatives having 3,5-Difluorophenyl group at the carbon side of difluoramethyleneoxy group ((1) under bar) have high dielectric anisotropy and low viscosity, and the derivatives having 1, 4-cyclohexylene group at the carbon side of difluoromethyleneoxy group ((2) under bar) have good balance of their physical properties. Moreover, (1) under bar and (2) under bar indicate high voltage holding ratio. Therefore, a novel series of the compounds having a difluoromethyleneoxy linkage group is an eminently suitable material that can lower driving voltage and achieve quicker response time of the AM-LCDs.

  DOI：

  10.1080/15421400490434919

文献信息

• HERSTELLUNG VON FLÜSSIGKRISTALLEN MIT CF20-BRÜCKE
  申请人：Merck Patent GmbH

  公开号：EP1259503B1

  公开（公告）日：2007-09-12
• Synthesis and Properties of Novel Liquid Crystalline Compounds having a Difluoromethyleneoxy Moiety as a Linkage Group
  作者：Shuichi Matsui、Tomoyuki Kondo、Kouki Sago

  DOI：10.1080/15421400490434919

  日期：2004.1

  Novel liquid crystal compounds having a difluoromethyleneoxy group as a linkage group have been prepared by the new synthetic method using dibromo-difluoromethane in good yield. From. the results of physical property measurements; i.e., transition temperature, dielectric anisotropy (Deltaepsilon), birefringence (Deltan) and viscosity, it becomes obvious that the derivatives having 3,5-Difluorophenyl group at the carbon side of difluoramethyleneoxy group ((1) under bar) have high dielectric anisotropy and low viscosity, and the derivatives having 1, 4-cyclohexylene group at the carbon side of difluoromethyleneoxy group ((2) under bar) have good balance of their physical properties. Moreover, (1) under bar and (2) under bar indicate high voltage holding ratio. Therefore, a novel series of the compounds having a difluoromethyleneoxy linkage group is an eminently suitable material that can lower driving voltage and achieve quicker response time of the AM-LCDs.