A composition for application to hair or scalp comprises (A) at least one compound selected from the group consisting of (i) forskolin and derivatives thereof and (ii) peptides having a basic skeletal structure represented by the following general formula (I):
-P-Glu-His-Q-Arg-Trp-Gly-Lys- (I)
(wherein P represents an L-norleucine or L-methionine residue; Q represents a D- or L-phenylalanine residue; and Glu, His, Arg, Trp, Gly and Lys are L-glutamic acid, L-histidine, L-arginine, L-tryptophan, glycine and L-lysine residues respectively); or the component A and (B) at least one compound selected from the group consisting of aliphatic acids, alcohols and derivatives thereof having an odd number of carbon atoms. The composition for hair or scalp exhibits excellent effect of preventing graying of the hair and restoring grayed hair to its natural color upon externally applied to the scalp and is highly safe as regards to the possibility of causing skin damage. Therefore, the composition can be widely used in various forms capable of being externally applied to the scalp.
一种用于头发或头皮的组合物包含(A)至少一种选自以下组别的化合物:(i) 福斯克林及其衍
生物和(ii)具有以下通式(I)所代表的基本骨架结构的肽:
-P-Glu-His-Q-Arg-Trp-Gly-Lys- (I)
(其中 P 代表
L-正亮氨酸或
L-蛋氨酸残基;Q 代表 D-或
L-苯丙氨酸残基;Glu、His、Arg、Trp、Gly 和 Lys 分别代表
L-谷氨酸、
L-组氨酸、
L-精氨酸、
L-色氨酸、甘
氨酸和
L-赖氨酸残基);或组分 A 和 (B) 至少一种选自具有奇数个碳原子的脂肪族酸、醇及其衍
生物的化合物。这种用于头发或头皮的组合物在外部涂抹到头皮上时,具有防止头发变白和使变白的头发恢复本色的卓越效果,而且在造成皮肤损伤的可能性方面非常安全。因此,该组合物可以以各种形式广泛应用于头皮。