4,5-dimethyl-4-cyclohexane-1,2-dicarboxylic acid anhydride

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异苯并呋喃
• 英文名称: 4,5-dimethyl-4-cyclohexane-1,2-dicarboxylic acid anhydride
• 英文别名: 5,6-Dimethyl-3a,4,5,6,7,7a-hexahydro-2-benzofuran-1,3-dione
• 化学式: C₁₀H₁₄O₃
• 分子量: 182.219
• InChiKey: ADGCNQTUYXBXBY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  13
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  43.4
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  5,6-二甲基-3a,4,7,7a-四氢-2-苯并呋喃-1,3-二酮 在 5%-palladium/activated carbon 、 氢气 作用下， 以 乙酸乙酯 为溶剂， 20.0 ℃ 、689.49 kPa 条件下， 反应 10.0h， 以98%的产率得到4,5-dimethyl-4-cyclohexane-1,2-dicarboxylic acid anhydride
  参考文献：
  名称：

  사이클릭카복실산 유도체, 이의 제조방법 및 이를 함유하는 관절염 예방 및 치료용 약학적 조성물

  摘要：

  本发明涉及一种循环羰基酸衍生物，其用化学式1表示，涉及其在药学上可接受的盐、水合物或溶剂化合物，由于具有抑制酪氨酸激酶的特性，因此含有其作为有效成分的药学组合物可用于预防和治疗关节炎：化学式1中，R，R，R，R，X，X，Y，Z，A，B和如规范中所定义。

  公开号：

  KR20200061428A

文献信息

• ALPHA-HYDROXYKETONES
  申请人：Dietliker Kurt

  公开号：US20100104979A1

  公开（公告）日：2010-04-29

  Compounds of the Formula (I) wherein x is an integer from 1-4; p is an integer from 1-3; q is an integer from 0-3; Ar is phenyl, naphthyl, anthryl or phenanthryl each of which optionally is substituted by one or more Cl, CN, OR 5 , C 3 -C 5 alkenyl or C 1 -C 6 alkyl which optionally is substituted by one or more OR 6 , COOR or halogen; R 1 if x is 1, is OR S , O—X + , NR 8 R 9 , C 1 -C 20 alkyl optionally substituted by one or more COOR 10 , or is C 2 -C 20 alkyl interrupted by one ore more O, or is C 2 -C 5 alkenyl or phenyl-C 1 -C 4 alkyl; R 1 if x is 2, is for example C 1 -C 20 alkylene; R 1 if x is 3, is for example a tri-valent radical; R 1 if x is 4, is for example a tetravalent radical; R 2 and R 3 are hydrogen or C 1 -C 8 alkyl, or R 2 and R 3 together are O, C 1 -C 3 alkylene or CH═CH; R 4 is C 1 -C 4 alkyl; R 5 , R 6 , R 7 , R 8 , R 9 and R 10 are for example hydrogen or C 1 -C 4 alkyl; and X is a x-valent cationic counter ion; are in particular suitable as photoinitiators for the curing with UV-A light (320-450 nm).

  化合物的公式（I），其中x是1-4之间的整数；p是1-3之间的整数；q是0-3之间的整数；Ar是苯基，萘基，蒽基或苊基，每个都可以选择性地被一个或多个Cl，CN，OR5，C3-C5烯基或C1-C6烷基取代，这些烷基可以选择性地被一个或多个OR6，COOR或卤素取代；如果x为1，则R1为ORS，O-X+，NR8R9，C1-C20烷基，可以选择性地被一个或多个COOR10取代，或者是被一个或多个O中断的C2-C20烷基，或者是C2-C5烯基或苯基-C1-C4烷基；如果x为2，则R1例如为C1-C20烷基；如果x为3，则R1例如为三价基团；如果x为4，则R1例如为四价基团；R2和R3为氢或C1-C8烷基，或者R2和R3一起为O，C1-C3亚烷基或CH═CH；R4为C1-C4烷基；R5，R6，R7，R8，R9和R10例如为氢或C1-C4烷基；X为x价阳离子对离子。这些化合物特别适用于使用UV-A光（320-450 nm）进行固化的光引发剂。
• METAL SALT OF ALICYCLIC DICARBOXYLIC ACID HAVING EXCELLENT DISPERSIBILITY IN POLYOLEFIN RESIN, PRODUCTION METHOD FOR SAID METAL SALT OF ALICYCLIC DICARBOXYLIC ACID, CRYSTAL NUCLEATOR FOR POLYOLEFIN RESIN CONTAINING SAID METAL SALT OF ALICYCLIC DICARBOXYLIC ACID, CRYSTAL NUCLEATOR COMPOSITION CONTAINING SAID CRYSTAL NUCLEATOR, POLYOLEFIN RESIN COMPOSITION, AND POLYOLEFIN RESIN MOLDED ARTICLE
  申请人：New Japan Chemical Co., Ltd.

  公开号：EP3851432A1

  公开（公告）日：2021-07-21

  The purpose of the present invention is to provide a metal salt of an alicyclic dicarboxylic acid which has excellent dispersibility in polyolefin resins, and is thus excellent in crystallinity improving effect that is essential performance as a crystal nucleating agent for polyolefin resins, regardless of processing conditions; a method for producing the metal salt of an alicyclic dicarboxylic acid; a crystal nucleating agent containing the metal salt of an alicyclic dicarboxylic acid; a crystal nucleating agent composition for polyolefin resins containing the crystal nucleating agent and a fatty acid metal salt; a polyolefin resin composition containing the crystal nucleating agent; and a polyolefin resin molded article obtained using the polyolefin resin composition as a raw material. Provided is a metal salt of an alicyclic dicarboxylic acid in which the alicyclic dicarboxylic acid is an alkyl substituent-containing cyclohexane-1,2-dicarboxylic acid, and the metal salt is a calcium salt, a hydroxyaluminum salt, a disodium salt, or a dilithium salt.

  本发明的目的是提供一种脂环族二羧酸金属盐，该金属盐在聚烯烃树脂中具有极佳的分散性，因此无论加工条件如何，作为聚烯烃树脂的晶核剂都具有优异的结晶度改善效果，而这是作为聚烯烃树脂晶核剂的基本性能；一种脂环族二羧酸金属盐的生产方法；含有脂环族二羧酸金属盐的成核剂；含有该成核剂和脂肪酸金属盐的聚烯烃树脂用成核剂组合物；含有该成核剂的聚烯烃树脂组合物；以及以该聚烯烃树脂组合物为原料获得的聚烯烃树脂成型品。本发明提供了一种脂环族二羧酸的金属盐，其中脂环族二羧酸为含烷基取代基的环己烷-1,2-二羧酸，金属盐为钙盐、羟基铝盐、二钠盐或二锂盐。
• Imide derivatives, their production and use
  申请人：SUMITOMO PHARMACEUTICALS COMPANY, LIMITED

  公开号：EP0196096B1

  公开（公告）日：1992-04-22
• ISIDZUMI, KIKUO;YASUNORI, FUDZIO;MARUYAMA, ISAMU;KODZIMA, ATSUYUKI
  作者：ISIDZUMI, KIKUO、YASUNORI, FUDZIO、MARUYAMA, ISAMU、KODZIMA, ATSUYUKI

  DOI：——

  日期：——
• Succinimide derivatives and their production
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：EP0109562B1

  公开（公告）日：1987-09-02