1-(2,5-dimethylphenyl)adamantane

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-(2,5-dimethylphenyl)adamantane
• 英文别名: 1-(1-adamantyl)-2,5-dimethylbenzene
• 化学式: C₁₈H₂₄
• 分子量: 240.389
• InChiKey: AIVZPSIZXRRGQG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.1
• 重原子数：
  18
• 可旋转键数：
  1
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  1-溴金刚烷 、 对二甲苯 在 molybdenum hexacarbonyl 作用下， 反应 2.0h， 以86%的产率得到1-(2,5-dimethylphenyl)adamantane
  参考文献：
  名称：

  Alkylation of aromatic compounds with 1-bromoadamantane in the presence of metal complex catalysts

  摘要：

  Synthesis of aryladamantanes was performed by reaction of 1-bromoadamantane with aromatic compounds in the presence of metal complex catalysts containing Mo, Cr, W, Cu, and Co.

  DOI：

  10.1134/s1070428015110056

文献信息

• Development of highly efficient Friedel–Crafts alkylations with alcohols using heterogeneous catalysts under continuous-flow conditions
  作者：Koichiro Masuda、Yukiko Okamoto、Shun-ya Onozawa、Nagatoshi Koumura、Shū Kobayashi

  DOI：10.1039/d1ra04005g

  日期：——

  The development of Friedel-Crafts alkylations with alcohols under continuous-flow conditions using heterogeneous catalysts is reported. The reactivities and durabilities of the examined catalysts were systematically investigated, which showed that montmorillonite clay is the best catalyst for these reactions. A high turnover frequency of 9.0 × 102 h-1 was recorded under continuous-flow conditions,

  报道了使用非均相催化剂在连续流动条件下用醇进行傅克烷基化反应的进展。系统地研究了所检查催化剂的反应性和耐久性，结果表明蒙脱石粘土是这些反应的最佳催化剂。在连续流动条件下记录到 9.0 × 102 h-1 的高周转频率，连续运行成功维持一周以上。
• Alkylation of aromatic compounds with 1-bromoadamantane in the presence of metal complex catalysts
  作者：R. I. Khusnutdinov、N. A. Shchadneva、L. F. Khisamova

  DOI：10.1134/s1070428015110056

  日期：2015.11

  Synthesis of aryladamantanes was performed by reaction of 1-bromoadamantane with aromatic compounds in the presence of metal complex catalysts containing Mo, Cr, W, Cu, and Co.