2,6-dihydro-2,5,11-trimethyl-1H-pyridazino[4,5-b]carbazol-1-one

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: 2,6-dihydro-2,5,11-trimethyl-1H-pyridazino[4,5-b]carbazol-1-one
• 化学式: C₁₇H₁₅N₃O
• 分子量: 277.326
• InChiKey: AMRJLDZESNKHLM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.18
• 重原子数：
  21.0
• 可旋转键数：
  0.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  50.68
• 氢给体数：
  1.0
• 氢受体数：
  3.0

反应信息

• 作为产物：
  描述：

  1,4-dimethylpyrano<3,4-b>indol-3-one 、 5-乙基磺酰基-2-甲基哒嗪-3-酮 以 various solvent(s) 为溶剂， 反应 47.0h， 生成 2,6-dihydro-2,5,11-trimethyl-1H-pyridazino[4,5-b]carbazol-1-one 、 3,6-dihydro-3,5,11-trimethyl-4H-pyridazino[4,5-b]carbazol-4-one 、 5,12-dihydro-6,13-dimethylcarbazolo[3,2-b]carbazole 、 5,8-dihydro-6,13-dimethylcarbazolo[2,3-b]carbazole
  参考文献：
  名称：

  Diels-Alder Reaction of Pyrano[3,4-b]indolones with an Electron-deficient Pyridazinone: A New Pathway to Carbazole-fused Pyridazines

  摘要：

  Thermally induced [4+2] cycloaddition reactions of 5-ethanesulfonyl-2-methylpyridazin-3(2H)-one (2) with pyrano[3,4-b]indol-3(9H)-ones (1, 4) affords isomeric pyridazino[4,5-b]carbazolones (3a,b, 5a,b), the product ratio depending on the substitution pattern of the diene. Two carbazolocarbazoles (6, 7) were obtained as side products.

  DOI：

  10.3987/com-99-8695

文献信息

• Diels-Alder Reaction of Pyrano[3,4-b]indolones with an Electron-deficient Pyridazinone: A New Pathway to Carbazole-fused Pyridazines
  作者：Norbert Haider、Johann Käferböck、Péter Mátyus

  DOI：10.3987/com-99-8695

  日期：——

  Thermally induced [4+2] cycloaddition reactions of 5-ethanesulfonyl-2-methylpyridazin-3(2H)-one (2) with pyrano[3,4-b]indol-3(9H)-ones (1, 4) affords isomeric pyridazino[4,5-b]carbazolones (3a,b, 5a,b), the product ratio depending on the substitution pattern of the diene. Two carbazolocarbazoles (6, 7) were obtained as side products.