N-(4-Hexyloxy-phenyl)-guanidine

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: N-(4-Hexyloxy-phenyl)-guanidine
• 英文别名: 1-(4-Hexoxyphenyl)guanidine；2-(4-hexoxyphenyl)guanidine
• 化学式: C₁₃H₂₁N₃O
• 分子量: 235.329
• InChiKey: AMXSRQWQNIJWTA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  17
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  73.6
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  氰胺 、 4-(hexyloxy)anilinium chloride 反应 0.25h， 生成 N-(4-Hexyloxy-phenyl)-guanidine
  参考文献：
  名称：

  Synthesis and in vitro antifungal activity of 4-substituted phenylguanidinium salts

  摘要：

  A series of 4-substituted phenylguanidinium derivatives was synthesized and its antimicrobial activity was evaluated in vitro against eight potentially pathogenic strains of fungi.

  DOI：

  10.1016/j.farmac.2004.03.001

文献信息

• Synthesis and in vitro antifungal activity of 4-substituted phenylguanidinium salts
  作者：Gabriela Braunerová、Vladimír Buchta、Luis Silva、Jiří Kuneš、Karel Palát

  DOI：10.1016/j.farmac.2004.03.001

  日期：2004.6

  A series of 4-substituted phenylguanidinium derivatives was synthesized and its antimicrobial activity was evaluated in vitro against eight potentially pathogenic strains of fungi.