1-[(4-iodophenyl)ethynyl]-4-[(4-methoxyphenyl)ethynyl]benzene

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 1-[(4-iodophenyl)ethynyl]-4-[(4-methoxyphenyl)ethynyl]benzene
• 英文别名: 1-iodo-4-[2-[4-[2-(4-methoxyphenyl)ethynyl]phenyl]ethynyl]benzene
• 化学式: C₂₃H₁₅IO
• 分子量: 434.276
• InChiKey: AXJPVYAPANOUJQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.1
• 重原子数：
  25.0
• 可旋转键数：
  1.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.04
• 拓扑面积：
  9.23
• 氢给体数：
  0.0
• 氢受体数：
  1.0

反应信息

• 作为反应物：
  描述：

  、 1-[(4-iodophenyl)ethynyl]-4-[(4-methoxyphenyl)ethynyl]benzene 在 1,1'-双(二苯基膦)二茂铁 、 tris-(dibenzylideneacetone)dipalladium(0) 、 copper(l) iodide 、 三乙胺 作用下， 以 四氢呋喃 为溶剂， 反应 16.0h， 以59%的产率得到
  参考文献：
  名称：

  基于平面手性 [2.2] 对环芳烷的 †- 和 ‡- 形分子的合成和手性特性

  摘要：

  通过化学选择性 Sonogashira-Hagihara 偶联，合成了两种基于平面手性 4,7,12,15-四取代 [2.2] 对环芳的光学活性分子。一个是†形...

  DOI：

  10.1246/bcsj.20200160
• 作为产物：
  描述：

  4-(4-iodophenyl)-2-methyl-3-butyn-2-ol 在 sodium hydroxide 、 copper(l) iodide 、 四(三苯基膦)钯 作用下， 以 三乙胺 、 甲苯 为溶剂， 反应 19.5h， 生成 1-[(4-iodophenyl)ethynyl]-4-[(4-methoxyphenyl)ethynyl]benzene
  参考文献：
  名称：

  Synthesis of nanometer-sized homo- and heteroorganometallic tripodaphyrins

  摘要：

  Tripodaphyrins are tetrahedral or pyramidal assemblies in which a porphyrin macrocycle situated on the top of the molecule is ''supported'' by three ''legs'' consisting of linear arrays of covalently linked rigid constitutive elements. The edge-length at the ''base'' of the molecules which have been synthesized until now lies in the range from 3.2 to 6.5 nm. In some tripodaphyrins (3a-c) the chromophore situated on the top of the molecule differs on the complexed metal ion from the other three, which are located at the ends of the ''legs''. Owing to the dimensions of the molecules, no intramolecular interaction between the chromophores is observed, even in the presence of a paramagnetic Cu(II) chelate. (C) 1997 Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4020(97)00380-3

文献信息

• Synthesis of nanometer-sized homo- and heteroorganometallic tripodaphyrins
  作者：Olivier Mongin、Albert Gossauer

  DOI：10.1016/s0040-4020(97)00380-3

  日期：1997.5

  Tripodaphyrins are tetrahedral or pyramidal assemblies in which a porphyrin macrocycle situated on the top of the molecule is ''supported'' by three ''legs'' consisting of linear arrays of covalently linked rigid constitutive elements. The edge-length at the ''base'' of the molecules which have been synthesized until now lies in the range from 3.2 to 6.5 nm. In some tripodaphyrins (3a-c) the chromophore situated on the top of the molecule differs on the complexed metal ion from the other three, which are located at the ends of the ''legs''. Owing to the dimensions of the molecules, no intramolecular interaction between the chromophores is observed, even in the presence of a paramagnetic Cu(II) chelate. (C) 1997 Elsevier Science Ltd.
• Synthesis and Chiroptical Properties of †- and ‡-Shaped Molecules Based on Planar Chiral [2.2]Paracyclophane
  作者：Yusaku Sasai、Ryo Inoue、Yasuhiro Morisaki

  DOI：10.1246/bcsj.20200160

  日期：2020.10.15

  Two types of optically active molecules based on planar chiral 4,7,12,15-tetrasubstituted [2.2]paracyclophane were synthesized through chemoselective Sonogashira-Hagihara coupling. One is a †-shape...

  通过化学选择性 Sonogashira-Hagihara 偶联，合成了两种基于平面手性 4,7,12,15-四取代 [2.2] 对环芳的光学活性分子。一个是†形...