三苯基四氮唑 | 902-00-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 中文名称: 三苯基四氮唑
• 中文别名: 2H-四唑正离子,2,3,5-三苯基-
• 英文名称: 2,3,5-triphenyltetrazolium
• 英文别名: Triphenyltetrazolium；2,3,5-triphenyltetrazol-2-ium
• CAS: 902-00-1
• 化学式: C₁₉H₁₅N₄
• mdl: MFCD00476617
• 分子量: 299.355
• InChiKey: LNOBZXNCABUBKK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.4
• 重原子数：
  23
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  34.6
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• Cardioprotective tocopherol analogs
  申请人：MERRELL DOW PHARMACEUTICALS INC.

  公开号：EP0369083A1

  公开（公告）日：1990-05-23

  This invention relates to quatenary ammonium salts of certain 2H-1-benzopyran derivatives, to intermediates and proces­ses useful for their preparation, to their free-radical scavenger and cellular protective properties and to their end-use applica­tion as therapeutic agents.

  这项发明涉及某些2H-1-苯并吡喁衍生物的季铵盐，以及用于它们的制备的中间体和工艺，它们的自由基清除剂和细胞保护性能，以及它们作为治疗剂的最终应用。
• COMPLEX COMPOUND AND OPTICAL RECORDING MEDIUM CONTAINING SAME
  申请人：KH NEOCHEM CO., LTD.

  公开号：US20130123494A1

  公开（公告）日：2013-05-16

  The present invention provides a complex compound, etc., which has superior moisture- and heat-resistances, etc. and is used for an optical recording medium, including: a compound represented by Formula (I) below [in the formula, R 1 represents an alkyl group which may have one or more substituents, etc., R 2 represents a cyano group, etc., R 3 represents an alkyl group which may have one or more substituents, etc., R 4 represents a hydrogen atom, etc., R 5 represents Formula (III) (in the formula, the ring A represents a heterocycle which may have one or more substituents, wherein the heterocycle is any one selected from a pyrimidine ring, a tetrazole ring, etc.)]; a metal; and any one ion selected from the group consisting of an ion formed by addition of one or more protons to an amine, an ammonium ion and a quaternary ammonium ion.

  本发明提供了一种具有优越的湿热性能等特性的复合物等，用于光记录介质，包括：下式中所表示的化合物（在该式中，R1代表一个可能具有一个或多个取代基的烷基基团等，R2代表一个氰基等，R3代表一个可能具有一个或多个取代基的烷基基团等，R4代表一个氢原子等，R5代表下式（III）（在该式中，环A代表一个可能具有一个或多个取代基的杂环，其中该杂环是从嘧啶环、四唑环等中任选的任一环）]；一种金属；以及从由一个或多个质子加到胺上形成的离子、铵离子和季铵离子组成的群体中选择的任一离子。
• METHOD AND DEVICE FOR THE DETECTION OF SULPHUR CONTAINING SPECIES
  申请人：Fallis Ian

  公开号：US20130224873A1

  公开（公告）日：2013-08-29

  A method is provided for detecting sulphur-containing species (such as thiophosphorous esters, in particular phosphorylating agents), in which a suspected sulphur-containing species is brought into contact with a tetrazolium compound in the presence of base, typically at a pH of at least 8. A device, kit and tetrazolium compounds for use in such a method are also disclosed.

  提供了一种用于检测含硫物质（如噻磷酯酯，特别是磷酰化剂）的方法，其中将疑似含硫物质与四唑化合物在碱的存在下接触，通常在至少为8的pH下。还公开了用于此类方法的装置、工具包和四唑化合物。
• [EN] BENZOPYRAN DERIVATIVES SUBSTITUTED WITH SECONDARY AMINES INCLUDING IMIDAZOLE, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM<br/>[FR] DERIVES DE BENZOPYRANE SUBSTITUES PAR DES AMINES SECONDAIRES DONT IMIDAZOLE, PREPARATION ET COMPOSITIONS PHARMACEUTIQUES LES CONTENANT
  申请人：KOREA RES INST CHEM TECH

  公开号：WO2004014898A1

  公开（公告）日：2004-02-19

  The present invention relates to benzopyran derivatives substituted with secondary amines including imidazole, their preparation, and pharmaceutical compositions containing them. The present invention is pharmacologically useful for the treatment of cancer, rheumatoid arthritis, and diabetic retinopathies through anti-angiogenic properties, and also pharmacologically useful in the protection of heart and neuronal cells against ischemia-reperfusion injury or preserving organs.

  本发明涉及取代了次级胺（包括咪唑）的苯并吡喃衍生物，以及其制备方法和含有它们的药物组合物。本发明在药理学上可用于治疗癌症、类风湿性关节炎和糖尿病视网膜病变，通过抗血管生成的特性，同时在保护心脏和神经细胞免受缺血再灌注损伤或保存器官方面也具有药理学上的用途。
• [EN] SK AND IK CHANNEL AGONISTS FOR TREATMENT OF HEART FAILURE<br/>[FR] AGENTS AGONISTES DES CANAUX SK ET IK POUR LE TRAITEMENT DE L'INSUFFISANCE CARDIAQUE
  申请人：UNIV COLUMBIA

  公开号：WO2016191294A1

  公开（公告）日：2016-12-01

  The present invention provides compounds that are improved potassium channel agonists. Pharmaceutical compositions including a pharmaceutically acceptable carrier and a compound of the present invention are also provided. Methods and kits for treating or ameliorating the effects of heart failure syndrome, high blood pressure and diabetes also are provided. Methods, kits and compositions which include compounds of the present invention also are provided.

  本发明提供了改进的钾通道激动剂化合物。还提供了包括药用可接受载体和本发明化合物的制药组合物。还提供了用于治疗或缓解心力衰竭综合症、高血压和糖尿病的方法和工具包。还提供了包括本发明化合物的方法、工具包和组合物。

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