S-ethyl-tetramethylthiouronium triflate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磺酸及其衍生物
• 英文名称: S-ethyl-tetramethylthiouronium triflate
• 英文别名: N,N,N',N'-tetramethyl-S-ethylisothiouronium triflate；S-ethyl-N,N,N',N'-tetramethylisothiouronium triflate；[Dimethylamino(ethylsulfanyl)methylidene]-dimethylazanium;trifluoromethanesulfonate
• 化学式: CF₃O₃S*C₇H₁₇N₂S
• 分子量: 310.362
• InChiKey: BNRWTFWSAUZSQI-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  0.98
• 重原子数：
  18
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  97.1
• 氢给体数：
  0
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  S-ethyl-tetramethylthiouronium triflate 、 tris(pentafluoroethyl)trifluorophosphoric acid 以 水 为溶剂， 以89.8%的产率得到S-ethyl-tetramethylthiouronium tris(pentafluoroethyl)trifluorophosphate
  参考文献：
  名称：

  [DE] IONISCHE FLÜSSIGKEITEN MIT URONIUM- ODER THIOURONIUM-KATIONEN
  [EN] IONIC LIQUID COMPRISING URONIUM CATIONS OR THIOURONIUM CATIONS
  [FR] LIQUIDES IONIQUES CONTENANT DES CATIONS D'URONIUM OU DE THIOURONIUM

  摘要：

  这项发明涉及具有硫脲或尿素阳离子的盐，它们的制备方法以及它们作为离子液体的用途。

  公开号：

  WO2004106287A1
• 作为产物：
  描述：

  四甲基硫脲 、 三氟甲烷磺酸乙酯 以 二氯甲烷 为溶剂， 反应 0.67h， 以99.5%的产率得到S-ethyl-tetramethylthiouronium triflate
  参考文献：
  名称：

  [DE] IONISCHE FLÜSSIGKEITEN MIT URONIUM- ODER THIOURONIUM-KATIONEN
  [EN] IONIC LIQUID COMPRISING URONIUM CATIONS OR THIOURONIUM CATIONS
  [FR] LIQUIDES IONIQUES CONTENANT DES CATIONS D'URONIUM OU DE THIOURONIUM

  摘要：

  这项发明涉及具有硫脲或尿素阳离子的盐，它们的制备方法以及它们作为离子液体的用途。

  公开号：

  WO2004106287A1

文献信息

• Nitrogen-containing tricyclic compounds
  申请人：Yamada Rintaro

  公开号：US20060247266A1

  公开（公告）日：2006-11-02

  A novel compound represented by the following formula (1) or a salt thereof [wherein R 1 , R 5 , R 6 , R 7 , and R 8 represent hydrogen atom, a halogen atom, hydroxyl group, an alkyl group, an alkenyl group and the like; X 1 . . . X 2 represents —CH(R 2 )—CH(R 3 )—, —CH(R 2 )—CH(R 3 )—CH(R 4 )—, —C(R 2 )═C(R 3 )—, or —C(R 2 )═C(R 3 )—CH(R 4 )—(R 2 , R 3 , and R 4 represent hydrogen atom, or an alkyl group); A 1 , A 11 , A 2 , and A 21 represent hydrogen atom, or an alkyl group; Y represents —CH(A 3 )-, —CH(A 3 )-C(A 4 )(A 41 )-, —CH(A 3 )-C(A 4 )(A 41 )-C(A 5 )(A 51 )-, or a single bond (A 3 , A 4 , A 41 , A 5 , and A 51 represent hydrogen atom, or an alkyl group), and Z represents hydroxyl group, or —N(A 6 )(A 61 )(A 6 represents hydrogen atom, or an alkyl group, and A 61 represents hydrogen atom, an alkyl group, a substituted alkyl group and the like)], having an action of potently inhibiting phosphorylation of myosin regulatory light chain.

  以下式（1）表示的新化合物或其盐[其中R1、R5、R6、R7和R8代表氢原子、卤素原子、羟基、烷基、烯基等；X1...X2代表—CH(R2)—CH(R3)—、—CH(R2)—CH(R3)—CH(R4)—、—C(R2)=C(R3)—或—C(R2)=C(R3)—CH(R4)—(R2、R3和R4代表氢原子或烷基)；A1、A11、A2和A21代表氢原子或烷基；Y代表—CH(A3)-、—CH(A3)-C(A4)(A41)-、—CH(A3)-C(A4)(A41)-C(A5)(A51)-或单一键（A3、A4、A41、A5和A51代表氢原子或烷基），Z代表羟基或—N(A6)(A61)(A6代表氢原子或烷基，A61代表氢原子、烷基、取代烷基等)]具有强烈抑制肌球蛋白调节轻链磷酸化的作用。
• PROCESS FOR THE PREPARATION OF ONIUM SALTS WITH ALKYL- OR ARYLSULFONATE ANIONS OR ALKYL- OR ARYLCARBOXYLATE ANIONS HAVING A LOW HALIDE CONTENT
  申请人：Ignatyev Nikolai (Mykola)

  公开号：US20090253905A1

  公开（公告）日：2009-10-08

  The invention relates to a method for producing onium salts comprising alkyl anions or aryl sulfonate anions or alkyl carboxylate anions or acryl carboxylate anions by reacting an onium halide with an alkyl silyl ester or trialkyl silyl ester of an alkyl sulfonic acid or aryl sulfonic acid or an alkyl carboxylic acid or aryl carboxylic acid or the anhydrides thereof.

  本发明涉及一种生产含有烷基阴离子或芳基磺酸盐阴离子或烷基羧酸盐阴离子或丙烯酸盐阴离子的离子盐的方法，其通过将离子卤化物与烷基硅酯或烷基磺酸或芳基磺酸的三烷基硅酯或烷基羧酸或芳基羧酸或其酐进行反应而得到。
• NITROGENEOUS TRICYCLIC COMPOUND
  申请人：Asahi Kasei Pharma Corporation

  公开号：EP1829876A1

  公开（公告）日：2007-09-05

  A novel compound represented by the following formula (1) or a salt thereof [wherein R1, R5, R6, R7, and R8 represent hydrogen atom, a halogen atom, hydroxyl group, an alkyl group, an alkenyl group and the like; X1···X2 represents -CH(R2)-CH(R3)-, -CH(R2)-CH(R3)-CH(R4)-, -C(R2)=C(R3)-, or -C(R2)=C(R3)-CH(R4)- (R2, R3, and R4 represent hydrogen atom, or an alkyl group); A1, A11, A2, and A21 represent hydrogen atom, or an alkyl group; Y represents -CH(A3)-, -CH(A3)-C(A4)(A41)-, -CH(A3)-C(A4)(A41)-C(A5)(A51)-, or a single bond (A3, A4, A41, A5, and A51 represent hydrogen atom, or an alkyl group), and Z represents hydroxyl group, or -N(A6)(A61) (As represents hydrogen atom, or an alkyl group, and A61 represents hydrogen atom, an alkyl group, a substituted alkyl group and the like)], having an action of potently inhibiting phosphorylation of myosin regulatory light chain.

  由下式(1)代表的新型化合物或其盐[其中R1、R5、R6、R7和R8代表氢原子、卤素原子、羟基、烷基、烯基等；X1---X2代表-CH(R2)-CH(R3)-、-CH(R2)-CH(R3)-CH(R4)-、-C(R2)=C(R3)-或-C(R2)=C(R3)-CH(R4)-（R2、R3和R4代表氢原子或烷基）；A1、A11、A2和A21代表氢原子或烷基；Y 代表 -CH(A3)-、-CH(A3)-C(A4)(A41)-、-CH(A3)-C(A4)(A41)-C(A5)(A51)- 或单键（A3、A4、A41、A5 和 A51 代表氢原子或烷基），Z 代表羟基或 -N(A6)(A61) （As 代表氢原子、或烷基，A61 代表氢原子、烷基、取代的烷基等）]，具有有效抑制肌球蛋白调节轻链磷酸化的作用。
• Process for the synthesis of carbamates using co2
  申请人：HUNTSMAN INTERNATIONAL LLC

  公开号：EP2011782A1

  公开（公告）日：2009-01-07

  Process for the synthesis of carbamate derivatives from amine compounds, alcohols and CO2 in the presence of ionic liquids and optionally in the presence of a base.

  在离子液体和碱的作用下，由胺化合物、醇和二氧化碳合成氨基甲酸酯衍生物的工艺。
• Electrochemical deblocking solution for electrochemical oligomer synthesis on an electrode array
  申请人：CustomArray, Inc.

  公开号：US10006131B1

  公开（公告）日：2018-06-26

  There is disclosed an electrochemical deblocking solution for use on an electrode microarray. There is further disclosed a method for electrochemical synthesis on an electrode array using the electrochemical deblocking solution. The solution and method are for removing acid-labile protecting groups for synthesis of oligonucleotides, peptides, small molecules, or polymers on a microarray of electrodes while substantially improving isolation of deblocking to active electrodes. The method comprises applying a voltage or a current to at least one electrode of an array of electrodes. The array of electrodes is covered by the electrochemical deblocking solution.

  本发明公开了一种用于电极微阵列的电化学解锁溶液。还进一步公开了一种使用该电化学解锁溶液在电极阵列上进行电化学合成的方法。该溶液和方法用于去除酸性保护基团，以便在电极微阵列上合成寡核苷酸、肽、小分子或聚合物，同时大幅提高与活性电极的解锁隔离度。该方法包括向电极阵列中的至少一个电极施加电压或电流。电极阵列被电化学解锁溶液覆盖。