5-(1H-pyrrol-1-yl)pentan-1-ol

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯
• 英文名称: 5-(1H-pyrrol-1-yl)pentan-1-ol
• 英文别名: N-(5-hydroxypentyl)pyrrole；5-(1-Pyrrolyl)pentan-1-ol；5-pyrrol-1-ylpentan-1-ol
• 化学式: C₉H₁₅NO
• 分子量: 153.224
• InChiKey: BOIVZQXPOBOLET-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  11
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  25.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  5-氨基-1-戊醇 、 1,4-丁烯二醇 在 palladium catalyst 作用下， 生成 5-(1H-pyrrol-1-yl)pentan-1-ol
  参考文献：
  名称：

  含钯微粒的聚[N-(5-羟基戊基)吡咯]薄膜包覆电极上有机化合物的电催化氢化

  摘要：

  制备了含有钯金属微粒的聚[N-(5-羟基戊基)吡咯]薄膜包覆碳纤维电极，并研究了其在有机化合物电化学加氢中的催化能力。该电极在析氢方面表现出高催化能力和强物理稳定性。通过使用该电极，在有机溶剂-缓冲溶液中对有机化合物进行电催化氢化，可以以高产率和电流效率有效形成氢化产物，如饱和化合物、氨基化合物和羟基化合物。此外，催化聚合物薄膜电极成功地应用于苄基的氢化脱保护和溴苯在电还原介质中的脱卤。

  DOI：

  10.1246/bcsj.70.837

文献信息

• Formation of <i>N</i>-Alkylpyrroles via Intermolecular Redox Amination
  作者：Nirmal K. Pahadi、Miranda Paley、Ranjan Jana、Shelli R. Waetzig、Jon A. Tunge

  DOI：10.1021/ja907357g

  日期：2009.11.25

  A wide variety of aldehydes, ketones, and lactols undergo redox amination when allowed to react with 3-pyrroline in the presence of a mild Bronsted acid catalyst. This reaction utilizes the inherent reducing power of 3-pyrroline to perform the equivalent of a reductive amination to form alkyl pyrroles. In doing so, the reaction avoids stoichiometric reducing agents that are typically associated with reductive aminations. Moreover, the redox amination protocol allows access to alkyl. pyrroles that cannot be made via standard reductive amination.
• [EN] NEW ANTICANCER COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM<br/>[FR] NOUVEAUX COMPOSES ANTICANCEREUX, PROCEDE DE PREPARATION DE CES DERNIERS ET COMPOSITIONS PHARMACEUTIQUES CONTENANT CES COMPOSES
  申请人：REDDYS LAB LTD DR

  公开号：WO2004069145A2

  公开（公告）日：2004-08-19

  The present invention relates to novel anticancer agents, their pharmaceutically acceptable salts, their geometrical isomers and their pharmaceutically acceptable compositions containing them. the present invention more particularly relates to novel quinazoline compounds, their pharmaceutically acceptable salts and their pharmaceutically acceptable compositions containing them. the novel quinazoline compounds have the general formula (I), where all symbols are as defined in the specification.
• Electrocatalytic Hydrogenation of Organic Compounds on a Poly[<i>N</i>-(5-hydroxypentyl)pyrrole] Film-Coated Electrode Incorporating Palladium Microparticles
  作者：Nobuhiro Takano、Akihito Nakade、Noboru Takeno

  DOI：10.1246/bcsj.70.837

  日期：1997.4

  carbon-fiber electrode incorporating palladium metal microparticles was prepared and the catalytic ability in the electrochemical hydrogenation of organic compounds was investigated. This electrode exhibited a high catalytic ability and a strong physical stability with respect to hydrogen evolution. By using this electrode, the electrocatalytic hydrogenation for organic compounds in an organic solvent–buffer

  制备了含有钯金属微粒的聚[N-(5-羟基戊基)吡咯]薄膜包覆碳纤维电极，并研究了其在有机化合物电化学加氢中的催化能力。该电极在析氢方面表现出高催化能力和强物理稳定性。通过使用该电极，在有机溶剂-缓冲溶液中对有机化合物进行电催化氢化，可以以高产率和电流效率有效形成氢化产物，如饱和化合物、氨基化合物和羟基化合物。此外，催化聚合物薄膜电极成功地应用于苄基的氢化脱保护和溴苯在电还原介质中的脱卤。