4-methoxyphenyl-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 4-methoxyphenyl-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside
• 化学式: C₁₉H₂₈O₁₁
• 分子量: 432.425
• InChiKey: BPOOSWJKJVLKEI-HSVXHRDBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.27
• 重原子数：
  30.0
• 可旋转键数：
  6.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.68
• 拓扑面积：
  167.53
• 氢给体数：
  6.0
• 氢受体数：
  11.0

反应信息

• 作为反应物：
  描述：

  4-methoxyphenyl-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside 在 盐酸 、 吡啶 、 三甲基硅咪唑 作用下， 以 水 为溶剂， 反应 1.08h， 生成 L-鼠李糖 、 葡萄糖
  参考文献：
  名称：

  A new aromatic glucoside from stem bark ofIllicium difengpiK.I.B. et K.I.M.

  摘要：

  A new aromatic glucoside, namely 4-methoxyphenyl-(6-deoxy--L-mannopyranosyl)--D-glucopyranoside (1), together with six known aromatic glucosides (2-7) were isolated from the stem bark of Illicium difengpi. The structures of these compounds were established by spectroscopic methods. The isolated aromatic glucosides were tested for anti-inflammatory activity. Compounds 1, 3 and 6 showed significant inhibitory effect on nuclear factor kappa B (NF-B) in RAW 264.7 macrophages induced by lipopolysaccharide.

  DOI：

  10.1080/14786419.2015.1004675

文献信息

• A new aromatic glucoside from stem bark of<i>Illicium difengpi</i>K.I.B. et K.I.M.
  作者：Chuntong Li、Zhijun Wu、Wansheng Chen

  DOI：10.1080/14786419.2015.1004675

  日期：2015.10.2

  A new aromatic glucoside, namely 4-methoxyphenyl-(6-deoxy--L-mannopyranosyl)--D-glucopyranoside (1), together with six known aromatic glucosides (2-7) were isolated from the stem bark of Illicium difengpi. The structures of these compounds were established by spectroscopic methods. The isolated aromatic glucosides were tested for anti-inflammatory activity. Compounds 1, 3 and 6 showed significant inhibitory effect on nuclear factor kappa B (NF-B) in RAW 264.7 macrophages induced by lipopolysaccharide.