(9Z,12Z)-9,12-Octadecadien-1-yl formate

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (9Z,12Z)-9,12-Octadecadien-1-yl formate
• 英文别名: [(9Z,12Z)-octadeca-9,12-dienyl] formate
• 化学式: C₁₉H₃₄O₂
• 分子量: 294.478
• InChiKey: XENSXNMABUFYQR-HZJYTTRNSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.3
• 重原子数：
  21
• 可旋转键数：
  16
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.74
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  亚油酸甲酯 在 lithium aluminium tetrahydride 作用下， 反应 5.0h， 生成 (9Z,12Z)-9,12-Octadecadien-1-yl formate
  参考文献：
  名称：

  Mammalian exocrine secretions: IX. Constituents of preorbital secretion of oribi,Ourebia, ourebi

  摘要：

  Using gas chromatography-mass spectrometry in conjunction with ancillary techniques such as chemical ionization with different reactant gases, determination of the position of double bonds by means of dimethyl disulfide derivatization, and finally gas chromatographic and mass spectrometric comparison with authentic synthetic material, 75 constituents were identified in the preorbital secretion of the male oribi, Ourebia ourebi. The secretion contains compounds with long-chain, unbranched structures similar to those found in many other preorbital secretions but with a finite volatility range, in contrast to the seemingly endlessly increasing chain lengths typical of other preorbital secretions.

  DOI：

  10.1007/bf02228320

文献信息

• [EN] AMPHIPHILE PRODRUGS<br/>[FR] PROMÉDICAMENTS AMPHIPHILES
  申请人：COMMW SCIENT IND RES ORG

  公开号：WO2010063080A1

  公开（公告）日：2010-06-10

  Amphiphilic prodrugs of general formula A-X are disclosed, wherein A is a biologically active agent or may be metabolised to a biologically active agent; and X is selected from the group consisting of R, or up to three R moieties attached to a linker, Y1, Y2 or Y3, wherein R is selected from a group consisting of alkyl, alkenyl, alkynyl, branched alkyl, branched alkenyl, branched alkynyl, substituted alkyl, substituted alkenyl and substituted alkynyl groups and their analogues; Y1 is a linker group which is covalently attached to an R group at one site and is attached to A at a further independent site; Y2 is a linker group which is covalently attached to two R groups at two independent sites and is attached to A at a further independent site; and Y3 is a linker group which is covalently attached to three R groups at three independent sites and is attached to A at a further independent site. Self-assembly of the amphiphilic prodrugs into reverse lyotropic phases, particularly hexagonal, cubic and sponge, is disclosed. In preferred embodiments A is dopamine or a 5- fluorouracil prodrug.
• Mammalian exocrine secretions: IX. Constituents of preorbital secretion of oribi,Ourebia, ourebi
  作者：W. -P. Mo、B. V. Burger、M. LeRoux、H. S. C. Spies

  DOI：10.1007/bf02228320

  日期：1995.8

  Using gas chromatography-mass spectrometry in conjunction with ancillary techniques such as chemical ionization with different reactant gases, determination of the position of double bonds by means of dimethyl disulfide derivatization, and finally gas chromatographic and mass spectrometric comparison with authentic synthetic material, 75 constituents were identified in the preorbital secretion of the male oribi, Ourebia ourebi. The secretion contains compounds with long-chain, unbranched structures similar to those found in many other preorbital secretions but with a finite volatility range, in contrast to the seemingly endlessly increasing chain lengths typical of other preorbital secretions.