vanillylmethylguaiacol

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: vanillylmethylguaiacol
• 英文别名: 3-(4-hydroxy-3-methoxybenzyl)-4-hydroxy-5-methoxybenzaldehyde；4-Hydroxy-3-(4-hydroxy-3-methoxybenzyl)-5-methoxybenzaldehyde；4-hydroxy-3-[(4-hydroxy-3-methoxyphenyl)methyl]-5-methoxybenzaldehyde
• 化学式: C₁₆H₁₆O₅
• 分子量: 288.3
• InChiKey: BZQOZUXQDDSNLZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  21
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.19
• 拓扑面积：
  76
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  4-羟基-3-甲氧基苄醇 、 香草醛 在 sodium carbonate 作用下， 以 水 为溶剂， 以76%的产率得到vanillylmethylguaiacol
  参考文献：
  名称：

  Method for preparing a vanillin derivative

  摘要：

  一种制备式(I)的化合物的方法，该化合物是一种茴香醛衍生物，为二聚体类型，称为3-(4-羟基-3-甲氧基苯基)-4-羟基-5-甲氧基苯甲醛，该方法包括在碱存在下对茴香醛和茴香醇进行反应。

  公开号：

  US20140323769A1

文献信息

• The early oxidative biodegradation steps of residual kraft lignin models with laccase
  作者：Claudia Crestini、Dimitris S. Argyropoulos

  DOI：10.1016/s0968-0896(98)00173-4

  日期：1998.11

  A number of model compounds resembling the fundamental bonding patterns of residual kraft lignin, including a series of stilbenes, were incubated with laccase from Trametes versicolor in the presence and absence of delignification 'mediators' ABTS and HBT. The condensed kraft lignin model compounds seem to undergo initial degradation by laccase mainly via benzylic oxidation, demethylation and hydroxylation reactions. Phenolic 5-5', diphenylmethane and alpha-5 lignin models were found to be degraded mainly via side-chain oxidation reactions. Among the models studied, a phenolic stilbene was found to be the most reactive, yielding several products showing side-chain oxidation/transposition, demethoxylation and hydroxylation reactions. Non-phenolic 5-5', diphenylmethane and stilbene model compounds were found unreactive even in the presence of the laccase-mediator system. (C) 1998 Elsevier Science Ltd. All rights reserved.
• The reactivity of phenolic and non-phenolic residual kraft lignin model compounds with Mn(II)-peroxidase from Lentinula edodes
  作者：Claudia Crestini、Alessandro D'Annibale、Giovanni Giovannozzi Sermanni、Raffaele Saladino

  DOI：10.1016/s0968-0896(99)00303-x

  日期：2000.2

  Three phenolic model compounds representing bonding patterns of residual kraft lignin were incubated with manganese peroxidase from Lentinula edodes. Extensive degradation of all the phenolic models, mainly occurring via side-chain benzylic oxidation, was observed. Among the tested model compounds the diphenylmethane alpha-5 phenolic model was found to be the most reactive, yielding several products showing oxidation and fragmentation at the bridging position. The non-phenolic 5-5' biphenyl and 5-5' diphenylmethane models were found unreactive. (C) 2000 Elsevier Science Ltd. All rights reserved.
• PROCÉDÉ DE PRÉPARATION D'UN DÉRIVÉ DE VANILLINE
  申请人：Rhodia Operations

  公开号：EP2763947B1

  公开（公告）日：2016-02-10
• NATURAL VANILLIN COMPOSITIONS
  申请人：RHODIA OPERATIONS

  公开号：US20220264922A1

  公开（公告）日：2022-08-25

  The present invention relates to natural vanillin compositions comprising at least one compound chosen from 4-((4-hydroxy-3-methoxybenzyl)oxy)-3-methoxybenzaldehyde and 4-hydroxy-3-(4-hydroxy-3-methoxybenzyl)-5-methoxybenzaldehyde. The invention also relates to a process for obtaining natural vanillin compositions according to the invention.
• US8933274B2
  申请人：——

  公开号：US8933274B2

  公开（公告）日：2015-01-13