maltobionate

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: maltobionate
• 英文别名: D-maltobionate；(2R,3R,4R,5R)-2,3,5,6-tetrahydroxy-4-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexanoate
• 化学式: C₁₂H₂₁O₁₂
• 分子量: 357.292
• InChiKey: JYTUSYBCFIZPBE-QOKIMYEXSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -4.3
• 重原子数：
  24
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  220
• 氢给体数：
  8
• 氢受体数：
  12

反应信息

• 作为产物：
  描述：

  麦芽糖 在 potassium dihydrogenphosphate 、 corn steep liquor 、 polypepton 、 magnesium sulfate 、 尿素 、 calcium carbonate 、 yeast extract 作用下， 以 水 为溶剂， 反应 48.0h， 生成 maltobionate
  参考文献：
  名称：

  A novel enzymic determination of maltobionate

  摘要：

  DOI：

  10.1016/0008-6215(96)00086-9

文献信息

• A novel carbohydrate:acceptor oxidoreductase from<i>Microdochium nivale</i>
  作者：Feng Xu、Elizabeth J. Golightly、Claus C. Fuglsang、Palle Schneider、Kyle R. Duke、Loi Lam、Søren Christensen、Kimberly M. Brown、Christel T. Jørgensen、Stephen H. Brown

  DOI：10.1046/j.1432-1327.2001.01982.x

  日期：2001.2

  A Microdochium nivale carbohydrate:acceptor oxidoreductase was purified, cloned, heterologously expressed, and characterized. The gene encoding the protein showed one intron, and the ORF showed a sequence with low homology (≤ 25% identity or 65% similarity) to other known flavin‐containing carbohydrate oxidases. The maturation of the protein required the cleavage of a tetrameric propeptide in addition to an 18 amino‐acid signal peptide. The enzyme was found to have a relative molecular mass of 55 000 Da, an isoelectric point of 9, and one FAD per protein. It could oxidize mono‐, oligo‐, or polymeric saccharides, and transfer their electrons to O2 or other acceptors. When d‐glucose served as electron‐donating substrate, an activity of 2 s−1 was observed at pH 5.5 and 23 °C. Among various oligosaccharides, the enzyme preferred tetrameric dextrins, indicating a favorable interaction of four linked glucose units with the substrate pocket. The unique structure and ability of oxidizing oligo/polymeric saccharides suggest a promising prospect of this enzyme for various industrial/medicinal applications.
• A novel enzymic determination of maltobionate
  作者：Y Shirokane

  DOI：10.1016/0008-6215(96)00086-9

  日期：1996.7.19