N,N'-(ethane-1,2-diyl)bis(2,5-dimethoxybenzenesulfonamide)

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N,N'-(ethane-1,2-diyl)bis(2,5-dimethoxybenzenesulfonamide)
• 英文别名: EBDMBS；N-[2-[(2,5-dimethoxyphenyl)sulfonylamino]ethyl]-2,5-dimethoxybenzenesulfonamide
• 化学式: C₁₈H₂₄N₂O₈S₂
• 分子量: 460.529
• InChiKey: GKBDHDBHBSGVRP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  30
• 可旋转键数：
  11
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  146
• 氢给体数：
  2
• 氢受体数：
  10

反应信息

• 作为产物：
  描述：

  2,5-二甲氧基苯磺酰氯 、 乙二胺 在 sodium carbonate 作用下， 以 水 为溶剂， 以78.4%的产率得到N,N'-(ethane-1,2-diyl)bis(2,5-dimethoxybenzenesulfonamide)
  参考文献：
  名称：

  Development of highly efficient Co2+ ions sensor based on N,N′-(ethane-1,2-diyl)bis(2,5-dimethoxybenzenesulfonamide) (EBDMBS) fabricated glassy carbon electrode

  摘要：

  Two bis-sulfonamides, N,N'-(ethane-1,2-diyl)bis(2,5-dimethoxybenzenesulfonamide) (EBDMBS) and N,N'-(ethane-1,2-diyl)bis(2-methoxy-5-bromobenzenesulfonamide) (EBMBBS) were synthesized to study their applications as heavy metal sensors. These molecules were prepared via very environment friendly methodology using diaminoethane and respective sulfonyl chlorides as reactants. Aromatic rings were ornamented with electron donating and withdrawing groups for comparison studies and to choose a best ligand for sensor preparation. The synthesized molecules were well characterized using UV/VIS, IR and NMR (H-1 & C-13) spectroscopic techniques. Finally, single crystal X-Ray diffraction studies prove the structures of our designed molecules. For the selective and sensitive potential sensor application, EBDMBS and EBMBBS were fabricated onto glassy carbon electrode (GCE; surface area, 0.0316 cm(2)) with conducting nafion binders to develop a Co2+ ions sensor in phosphate buffer phase. The fabricated ionic-sensor with EBDMBS/GCE is exhibited higher sensitivity, large-dynamic concentration ranges, long-term stability, and improved electrochemical performances towards cobalt ions. The calibration plot is linear (r(2) = 0.9891) over the large Co2+ concentration ranges (0.35 nM-3.5 mM). The sensitivity and detection limit is similar to 1.87 mu A mu M(-1)cm(-2) and similar to 0.17 +/- 0.02 nM (signal-to-noise ratio, at a SNR of 3) respectively. This novel effort is initiated a well-organize way of efficient cationic sensor development for toxic pollutants in environmental and health-care fields in large scales. (C) 2016 Elsevier B. V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2016.08.010

文献信息

• Development of highly efficient Co2+ ions sensor based on N,N′-(ethane-1,2-diyl)bis(2,5-dimethoxybenzenesulfonamide) (EBDMBS) fabricated glassy carbon electrode
  作者：Tahir Ali Sheikh、Muhammad Nadeem Arshad、Mohammed M. Rahman、Abdullah M. Asiri、Khalid A. Alamry

  DOI：10.1016/j.jorganchem.2016.08.010

  日期：2016.11

  Two bis-sulfonamides, N,N'-(ethane-1,2-diyl)bis(2,5-dimethoxybenzenesulfonamide) (EBDMBS) and N,N'-(ethane-1,2-diyl)bis(2-methoxy-5-bromobenzenesulfonamide) (EBMBBS) were synthesized to study their applications as heavy metal sensors. These molecules were prepared via very environment friendly methodology using diaminoethane and respective sulfonyl chlorides as reactants. Aromatic rings were ornamented with electron donating and withdrawing groups for comparison studies and to choose a best ligand for sensor preparation. The synthesized molecules were well characterized using UV/VIS, IR and NMR (H-1 & C-13) spectroscopic techniques. Finally, single crystal X-Ray diffraction studies prove the structures of our designed molecules. For the selective and sensitive potential sensor application, EBDMBS and EBMBBS were fabricated onto glassy carbon electrode (GCE; surface area, 0.0316 cm(2)) with conducting nafion binders to develop a Co2+ ions sensor in phosphate buffer phase. The fabricated ionic-sensor with EBDMBS/GCE is exhibited higher sensitivity, large-dynamic concentration ranges, long-term stability, and improved electrochemical performances towards cobalt ions. The calibration plot is linear (r(2) = 0.9891) over the large Co2+ concentration ranges (0.35 nM-3.5 mM). The sensitivity and detection limit is similar to 1.87 mu A mu M(-1)cm(-2) and similar to 0.17 +/- 0.02 nM (signal-to-noise ratio, at a SNR of 3) respectively. This novel effort is initiated a well-organize way of efficient cationic sensor development for toxic pollutants in environmental and health-care fields in large scales. (C) 2016 Elsevier B. V. All rights reserved.